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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
APOL1
All Species:
4.24
Human Site:
T59
Identified Species:
18.67
UniProt:
O14791
Number Species:
5
Phosphosite Substitution
Charge Score:
0.4
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14791
NP_001130012.1
398
43974
T59
L
G
D
W
A
A
G
T
M
D
P
E
S
S
I
Chimpanzee
Pan troglodytes
XP_001143991
549
59245
T212
L
G
N
P
A
A
G
T
M
N
P
E
S
S
I
Rhesus Macaque
Macaca mulatta
XP_001083192
617
67132
W281
E
P
P
W
T
A
N
W
P
V
L
K
S
S
I
Dog
Lupus familis
XP_853063
343
37276
H49
T
V
N
R
E
V
L
H
F
L
L
I
N
H
E
Cat
Felis silvestris
Mouse
Mus musculus
XP_139463
449
48380
E117
T
M
D
P
S
D
C
E
D
A
P
G
D
R
T
Rat
Rattus norvegicus
XP_235465
346
37070
E50
E
A
F
V
A
E
A
E
L
S
R
A
D
A
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
44.2
40.3
31.6
N.A.
35.6
35.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
56.2
48.7
49.5
N.A.
51.8
52.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
80
33.3
0
N.A.
13.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
40
13.3
N.A.
20
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
17
0
0
50
50
17
0
0
17
0
17
0
17
0
% A
% Cys:
0
0
0
0
0
0
17
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
34
0
0
17
0
0
17
17
0
0
34
0
17
% D
% Glu:
34
0
0
0
17
17
0
34
0
0
0
34
0
0
17
% E
% Phe:
0
0
17
0
0
0
0
0
17
0
0
0
0
0
0
% F
% Gly:
0
34
0
0
0
0
34
0
0
0
0
17
0
0
0
% G
% His:
0
0
0
0
0
0
0
17
0
0
0
0
0
17
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
17
0
0
50
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
17
0
0
0
% K
% Leu:
34
0
0
0
0
0
17
0
17
17
34
0
0
0
0
% L
% Met:
0
17
0
0
0
0
0
0
34
0
0
0
0
0
0
% M
% Asn:
0
0
34
0
0
0
17
0
0
17
0
0
17
0
0
% N
% Pro:
0
17
17
34
0
0
0
0
17
0
50
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
17
0
0
0
0
0
0
17
0
0
17
0
% R
% Ser:
0
0
0
0
17
0
0
0
0
17
0
0
50
50
0
% S
% Thr:
34
0
0
0
17
0
0
34
0
0
0
0
0
0
17
% T
% Val:
0
17
0
17
0
17
0
0
0
17
0
0
0
0
0
% V
% Trp:
0
0
0
34
0
0
0
17
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _