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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF3C All Species: 30.3
Human Site: T173 Identified Species: 51.28
UniProt: O14782 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14782 NP_002245.4 793 89454 T173 E L K E N P E T G V Y I K D L
Chimpanzee Pan troglodytes XP_001149366 793 89463 T173 E L K E N P E T G V Y I K D L
Rhesus Macaque Macaca mulatta XP_001084972 793 89433 T173 E L K E N P E T G V Y I K D L
Dog Lupus familis XP_849575 779 88618 T173 E L K E N P E T G V Y I K D L
Cat Felis silvestris
Mouse Mus musculus O35066 796 89940 T173 E L K E N P E T G V Y I K D L
Rat Rattus norvegicus O55165 796 89797 T173 E L K E N P E T G V Y I K D L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90640 1225 138905 K284 A L G E E N K K G G F V P Y R
Frog Xenopus laevis P28025 1060 119314 P181 R L Q M F D D P R N K R G V I
Zebra Danio Brachydanio rerio NP_001017849 759 86830 L183 E L K E N P E L G V Y V K D L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P46867 784 88189 S180 L E V R E R G S G V Y V P N L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P46873 699 78760 H173 Y V A G L S M H V C H D V P A
Sea Urchin Strong. purpuratus P46871 742 84184 T171 D L K E R P D T G V Y V K D L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P82266 1056 119250 K182 A A E E K Q K K P L P L M E D
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P48467 928 102392 Y176 V K G L L E I Y V S S V Q E V
Conservation
Percent
Protein Identity: 100 99.8 98.9 95.5 N.A. 94.9 95.9 N.A. N.A. 24.5 23.2 58.7 N.A. 43.1 N.A. 34.6 54.9
Protein Similarity: 100 100 99.3 96.7 N.A. 97.2 97.8 N.A. N.A. 38.2 41.5 73.6 N.A. 63.5 N.A. 50.8 72.7
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. N.A. 20 6.6 86.6 N.A. 26.6 N.A. 0 73.3
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 40 26.6 93.3 N.A. 46.6 N.A. 13.3 93.3
Percent
Protein Identity: N.A. N.A. N.A. 23.6 N.A. 26.6
Protein Similarity: N.A. N.A. N.A. 40.5 N.A. 44.7
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. 0
P-Site Similarity: N.A. N.A. N.A. 40 N.A. 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 8 8 0 0 0 0 0 0 0 0 0 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % C
% Asp: 8 0 0 0 0 8 15 0 0 0 0 8 0 58 8 % D
% Glu: 50 8 8 72 15 8 50 0 0 0 0 0 0 15 0 % E
% Phe: 0 0 0 0 8 0 0 0 0 0 8 0 0 0 0 % F
% Gly: 0 0 15 8 0 0 8 0 72 8 0 0 8 0 0 % G
% His: 0 0 0 0 0 0 0 8 0 0 8 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 8 0 0 0 0 43 0 0 8 % I
% Lys: 0 8 58 0 8 0 15 15 0 0 8 0 58 0 0 % K
% Leu: 8 72 0 8 15 0 0 8 0 8 0 8 0 0 65 % L
% Met: 0 0 0 8 0 0 8 0 0 0 0 0 8 0 0 % M
% Asn: 0 0 0 0 50 8 0 0 0 8 0 0 0 8 0 % N
% Pro: 0 0 0 0 0 58 0 8 8 0 8 0 15 8 0 % P
% Gln: 0 0 8 0 0 8 0 0 0 0 0 0 8 0 0 % Q
% Arg: 8 0 0 8 8 8 0 0 8 0 0 8 0 0 8 % R
% Ser: 0 0 0 0 0 8 0 8 0 8 8 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 50 0 0 0 0 0 0 0 % T
% Val: 8 8 8 0 0 0 0 0 15 65 0 36 8 8 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 0 0 0 8 0 0 65 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _