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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIF3C
All Species:
32.73
Human Site:
S227
Identified Species:
55.38
UniProt:
O14782
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14782
NP_002245.4
793
89454
S227
F
I
I
T
V
E
C
S
E
R
G
S
D
G
Q
Chimpanzee
Pan troglodytes
XP_001149366
793
89463
S227
F
I
I
T
V
E
C
S
E
R
G
S
D
G
Q
Rhesus Macaque
Macaca mulatta
XP_001084972
793
89433
S227
F
I
I
T
V
E
C
S
E
R
G
S
D
G
Q
Dog
Lupus familis
XP_849575
779
88618
S227
F
V
I
T
V
E
C
S
E
R
G
S
D
G
Q
Cat
Felis silvestris
Mouse
Mus musculus
O35066
796
89940
S227
F
V
I
T
V
E
C
S
E
R
G
S
D
G
Q
Rat
Rattus norvegicus
O55165
796
89797
S227
F
V
I
T
V
E
C
S
E
R
G
S
D
G
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90640
1225
138905
N430
I
I
V
T
E
Q
E
N
E
K
M
N
A
K
L
Frog
Xenopus laevis
P28025
1060
119314
K239
F
S
V
T
I
H
M
K
E
T
T
V
D
G
E
Zebra Danio
Brachydanio rerio
NP_001017849
759
86830
S237
F
V
I
T
I
E
C
S
E
M
G
I
D
G
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P46867
784
88189
C234
F
M
I
K
I
E
M
C
D
T
E
T
N
T
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P46873
699
78760
K227
T
G
S
I
R
M
G
K
L
N
L
V
D
L
A
Sea Urchin
Strong. purpuratus
P46871
742
84184
S225
F
I
I
T
I
E
C
S
E
L
G
V
D
G
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P82266
1056
119250
K246
F
S
I
T
I
H
I
K
E
A
T
P
E
G
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P48467
928
102392
S239
F
L
V
D
L
A
G
S
E
K
V
G
K
T
G
Conservation
Percent
Protein Identity:
100
99.8
98.9
95.5
N.A.
94.9
95.9
N.A.
N.A.
24.5
23.2
58.7
N.A.
43.1
N.A.
34.6
54.9
Protein Similarity:
100
100
99.3
96.7
N.A.
97.2
97.8
N.A.
N.A.
38.2
41.5
73.6
N.A.
63.5
N.A.
50.8
72.7
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
20
33.3
66.6
N.A.
20
N.A.
6.6
73.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
53.3
53.3
86.6
N.A.
53.3
N.A.
6.6
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.6
N.A.
26.6
Protein Similarity:
N.A.
N.A.
N.A.
40.5
N.A.
44.7
P-Site Identity:
N.A.
N.A.
N.A.
33.3
N.A.
20
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
N.A.
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
0
0
0
8
0
0
8
0
8
% A
% Cys:
0
0
0
0
0
0
58
8
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
0
0
8
0
0
0
72
0
0
% D
% Glu:
0
0
0
0
8
65
8
0
86
0
8
0
8
0
29
% E
% Phe:
86
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
0
0
0
15
0
0
0
58
8
0
72
8
% G
% His:
0
0
0
0
0
15
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
36
72
8
36
0
8
0
0
0
0
8
0
0
8
% I
% Lys:
0
0
0
8
0
0
0
22
0
15
0
0
8
8
0
% K
% Leu:
0
8
0
0
8
0
0
0
8
8
8
0
0
8
8
% L
% Met:
0
8
0
0
0
8
15
0
0
8
8
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
8
0
8
8
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% P
% Gln:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
43
% Q
% Arg:
0
0
0
0
8
0
0
0
0
43
0
0
0
0
0
% R
% Ser:
0
15
8
0
0
0
0
65
0
0
0
43
0
0
0
% S
% Thr:
8
0
0
79
0
0
0
0
0
15
15
8
0
15
0
% T
% Val:
0
29
22
0
43
0
0
0
0
0
8
22
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _