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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GNB5
All Species:
19.09
Human Site:
Y290
Identified Species:
26.25
UniProt:
O14775
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14775
NP_006569.1
395
43566
Y290
D
I
N
S
V
R
Y
Y
P
S
G
D
A
F
A
Chimpanzee
Pan troglodytes
XP_001151191
271
29444
P167
I
N
S
V
R
Y
Y
P
S
G
D
A
F
A
S
Rhesus Macaque
Macaca mulatta
XP_001085617
398
43946
Y293
D
I
N
S
V
R
Y
Y
P
S
G
D
A
F
A
Dog
Lupus familis
XP_851178
395
43521
Y290
D
I
N
S
V
R
Y
Y
P
S
G
D
A
F
A
Cat
Felis silvestris
Mouse
Mus musculus
P62881
395
43547
Y290
D
V
N
S
V
R
Y
Y
P
S
G
D
A
F
A
Rat
Rattus norvegicus
P62882
353
38713
P249
V
N
S
V
R
Y
Y
P
S
G
D
A
F
A
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511953
185
20110
R81
E
S
D
I
N
S
V
R
Y
Y
P
S
G
D
A
Chicken
Gallus gallus
XP_413801
395
43545
Y290
D
I
N
S
V
R
Y
Y
P
S
G
D
A
F
A
Frog
Xenopus laevis
P79959
340
37311
P236
I
N
A
I
C
F
F
P
N
G
N
A
F
A
T
Zebra Danio
Brachydanio rerio
Q6PH57
340
37267
P236
I
N
A
I
C
F
F
P
N
G
N
A
F
A
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P26308
340
37114
P236
I
N
A
V
T
F
F
P
N
G
Q
A
F
A
T
Honey Bee
Apis mellifera
XP_392638
349
38388
P245
V
N
S
V
K
F
H
P
G
G
D
A
V
A
T
Nematode Worm
Caenorhab. elegans
Q20636
356
39435
P252
I
N
T
V
R
F
H
P
N
G
D
A
F
A
T
Sea Urchin
Strong. purpuratus
XP_792481
354
39270
F249
D
I
N
A
V
R
F
F
P
S
G
D
G
F
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P49178
380
41696
G267
D
G
H
R
F
G
T
G
S
D
D
G
T
C
R
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P49177
377
40987
G264
F
P
D
G
Y
R
F
G
T
G
S
D
D
G
T
Baker's Yeast
Sacchar. cerevisiae
P18851
423
46563
Y314
T
F
S
L
F
R
G
Y
E
E
R
T
P
T
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
68.6
91.2
97.7
N.A.
99.2
88.8
N.A.
45.5
94.9
46.3
46.8
N.A.
46.5
62.2
57.9
63.5
Protein Similarity:
100
68.6
93.9
98.2
N.A.
100
89.3
N.A.
46.8
97.4
63
63.5
N.A.
61.7
74.9
72.4
78.2
P-Site Identity:
100
6.6
100
100
N.A.
93.3
6.6
N.A.
6.6
100
0
0
N.A.
0
0
0
73.3
P-Site Similarity:
100
20
100
100
N.A.
100
20
N.A.
20
100
6.6
6.6
N.A.
6.6
13.3
6.6
93.3
Percent
Protein Identity:
N.A.
37.7
N.A.
38.9
34.7
N.A.
Protein Similarity:
N.A.
58.7
N.A.
58.7
55.7
N.A.
P-Site Identity:
N.A.
6.6
N.A.
13.3
13.3
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
26.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
18
6
0
0
0
0
0
0
0
42
30
42
42
% A
% Cys:
0
0
0
0
12
0
0
0
0
0
0
0
0
6
0
% C
% Asp:
42
0
12
0
0
0
0
0
0
6
30
42
6
6
0
% D
% Glu:
6
0
0
0
0
0
0
0
6
6
0
0
0
0
0
% E
% Phe:
6
6
0
0
12
30
30
6
0
0
0
0
36
36
0
% F
% Gly:
0
6
0
6
0
6
6
12
6
48
36
6
12
6
0
% G
% His:
0
0
6
0
0
0
12
0
0
0
0
0
0
0
0
% H
% Ile:
30
30
0
18
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
6
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
6
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
42
36
0
6
0
0
0
24
0
12
0
0
0
0
% N
% Pro:
0
6
0
0
0
0
0
42
36
0
6
0
6
0
6
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
6
0
0
0
0
% Q
% Arg:
0
0
0
6
18
48
0
6
0
0
6
0
0
0
6
% R
% Ser:
0
6
24
30
0
6
0
0
18
36
6
6
0
0
12
% S
% Thr:
6
0
6
0
6
0
6
0
6
0
0
6
6
6
36
% T
% Val:
12
6
0
30
36
0
6
0
0
0
0
0
6
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
6
12
42
36
6
6
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _