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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GNB5
All Species:
23.33
Human Site:
T253
Identified Species:
32.08
UniProt:
O14775
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14775
NP_006569.1
395
43566
T253
A
P
S
E
T
G
N
T
F
V
S
G
G
C
D
Chimpanzee
Pan troglodytes
XP_001151191
271
29444
F130
P
S
E
T
G
N
T
F
V
S
G
G
C
D
K
Rhesus Macaque
Macaca mulatta
XP_001085617
398
43946
T256
A
P
S
E
T
G
N
T
F
V
S
G
G
C
D
Dog
Lupus familis
XP_851178
395
43521
T253
A
P
S
E
T
G
N
T
F
V
S
G
G
C
D
Cat
Felis silvestris
Mouse
Mus musculus
P62881
395
43547
T253
A
P
S
E
T
G
N
T
F
V
S
G
G
C
D
Rat
Rattus norvegicus
P62882
353
38713
F212
P
S
E
T
G
N
T
F
V
S
G
G
C
D
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511953
185
20110
G44
D
L
A
P
S
E
T
G
N
T
F
V
S
G
G
Chicken
Gallus gallus
XP_413801
395
43545
T253
A
P
S
E
T
G
N
T
F
V
S
G
G
C
D
Frog
Xenopus laevis
P79959
340
37311
F199
L
A
P
D
S
R
C
F
V
S
G
A
C
D
A
Zebra Danio
Brachydanio rerio
Q6PH57
340
37267
F199
L
A
P
D
T
R
L
F
V
S
G
A
C
D
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P26308
340
37114
F199
L
A
P
Q
C
K
T
F
V
S
G
A
C
D
A
Honey Bee
Apis mellifera
XP_392638
349
38388
F208
P
S
E
T
G
N
T
F
V
S
G
S
C
D
K
Nematode Worm
Caenorhab. elegans
Q20636
356
39435
F215
K
C
D
T
G
N
T
F
I
S
A
G
A
D
K
Sea Urchin
Strong. purpuratus
XP_792481
354
39270
T212
S
P
S
E
A
C
N
T
F
V
S
G
G
C
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P49178
380
41696
V230
S
G
S
C
D
T
T
V
R
L
W
D
I
R
I
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P49177
377
40987
S227
F
I
S
G
S
C
D
S
T
A
R
L
W
D
T
Baker's Yeast
Sacchar. cerevisiae
P18851
423
46563
R277
D
S
D
I
N
A
L
R
F
F
K
D
G
M
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
68.6
91.2
97.7
N.A.
99.2
88.8
N.A.
45.5
94.9
46.3
46.8
N.A.
46.5
62.2
57.9
63.5
Protein Similarity:
100
68.6
93.9
98.2
N.A.
100
89.3
N.A.
46.8
97.4
63
63.5
N.A.
61.7
74.9
72.4
78.2
P-Site Identity:
100
6.6
100
100
N.A.
100
6.6
N.A.
0
100
0
6.6
N.A.
0
0
6.6
80
P-Site Similarity:
100
6.6
100
100
N.A.
100
6.6
N.A.
13.3
100
13.3
13.3
N.A.
6.6
0
13.3
86.6
Percent
Protein Identity:
N.A.
37.7
N.A.
38.9
34.7
N.A.
Protein Similarity:
N.A.
58.7
N.A.
58.7
55.7
N.A.
P-Site Identity:
N.A.
6.6
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
20
N.A.
26.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
30
18
6
0
6
6
0
0
0
6
6
18
6
0
18
% A
% Cys:
0
6
0
6
6
12
6
0
0
0
0
0
36
36
0
% C
% Asp:
12
0
12
12
6
0
6
0
0
0
0
12
0
48
36
% D
% Glu:
0
0
18
36
0
6
0
0
0
0
0
0
0
0
0
% E
% Phe:
6
0
0
0
0
0
0
42
42
6
6
0
0
0
0
% F
% Gly:
0
6
0
6
24
30
0
6
0
0
36
53
42
6
6
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
6
0
6
0
0
0
0
6
0
0
0
6
0
6
% I
% Lys:
6
0
0
0
0
6
0
0
0
0
6
0
0
0
24
% K
% Leu:
18
6
0
0
0
0
12
0
0
6
0
6
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
6
0
% M
% Asn:
0
0
0
0
6
24
36
0
6
0
0
0
0
0
0
% N
% Pro:
18
36
18
6
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
6
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
12
0
6
6
0
6
0
0
6
0
% R
% Ser:
12
24
48
0
18
0
0
6
0
42
36
6
6
0
6
% S
% Thr:
0
0
0
24
36
6
42
36
6
6
0
0
0
0
6
% T
% Val:
0
0
0
0
0
0
0
6
36
36
0
6
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
6
0
6
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _