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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GNB5
All Species:
33.64
Human Site:
T177
Identified Species:
46.25
UniProt:
O14775
Number Species:
16
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14775
NP_006569.1
395
43566
T177
K
C
S
V
Y
P
L
T
F
D
K
N
E
N
M
Chimpanzee
Pan troglodytes
XP_001151191
271
29444
D55
S
V
Y
P
L
T
F
D
K
N
E
N
M
A
A
Rhesus Macaque
Macaca mulatta
XP_001085617
398
43946
T180
K
C
S
V
Y
P
L
T
F
D
K
N
E
N
M
Dog
Lupus familis
XP_851178
395
43521
T177
K
C
S
V
Y
P
L
T
F
D
K
N
E
N
M
Cat
Felis silvestris
Mouse
Mus musculus
P62881
395
43547
T177
K
C
S
V
Y
P
L
T
F
D
K
N
E
N
M
Rat
Rattus norvegicus
P62882
353
38713
D137
S
V
Y
P
L
T
F
D
K
N
E
N
M
A
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511953
185
20110
Chicken
Gallus gallus
XP_413801
395
43545
T177
K
C
S
V
Y
P
L
T
F
D
K
N
E
N
M
Frog
Xenopus laevis
P79959
340
37311
Y124
L
D
N
I
C
P
I
Y
N
L
K
T
R
E
G
Zebra Danio
Brachydanio rerio
Q6PH57
340
37267
Y124
L
D
N
I
C
S
I
Y
N
L
K
T
R
E
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P26308
340
37114
Y124
L
D
N
M
C
S
I
Y
N
L
K
T
R
E
G
Honey Bee
Apis mellifera
XP_392638
349
38388
S133
K
V
T
V
Y
P
L
S
Q
E
D
D
V
S
T
Nematode Worm
Caenorhab. elegans
Q20636
356
39435
S140
K
C
S
V
V
P
L
S
F
E
D
D
I
I
Q
Sea Urchin
Strong. purpuratus
XP_792481
354
39270
T137
K
C
S
V
Y
Q
L
T
Q
E
E
D
L
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P49178
380
41696
I152
G
N
M
P
V
S
R
I
L
T
G
H
K
G
Y
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P49177
377
40987
M151
G
T
V
P
V
S
R
M
L
T
G
H
R
G
Y
Baker's Yeast
Sacchar. cerevisiae
P18851
423
46563
S164
N
C
T
I
Y
R
V
S
K
E
N
R
V
A
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
68.6
91.2
97.7
N.A.
99.2
88.8
N.A.
45.5
94.9
46.3
46.8
N.A.
46.5
62.2
57.9
63.5
Protein Similarity:
100
68.6
93.9
98.2
N.A.
100
89.3
N.A.
46.8
97.4
63
63.5
N.A.
61.7
74.9
72.4
78.2
P-Site Identity:
100
6.6
100
100
N.A.
100
6.6
N.A.
0
100
13.3
6.6
N.A.
6.6
33.3
46.6
46.6
P-Site Similarity:
100
20
100
100
N.A.
100
20
N.A.
0
100
33.3
26.6
N.A.
26.6
66.6
66.6
73.3
Percent
Protein Identity:
N.A.
37.7
N.A.
38.9
34.7
N.A.
Protein Similarity:
N.A.
58.7
N.A.
58.7
55.7
N.A.
P-Site Identity:
N.A.
0
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
6.6
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
18
12
% A
% Cys:
0
48
0
0
18
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
18
0
0
0
0
0
12
0
30
12
18
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
24
18
0
30
18
0
% E
% Phe:
0
0
0
0
0
0
12
0
36
0
0
0
0
0
0
% F
% Gly:
12
0
0
0
0
0
0
0
0
0
12
0
0
12
18
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% H
% Ile:
0
0
0
18
0
0
18
6
0
0
0
0
6
6
0
% I
% Lys:
48
0
0
0
0
0
0
0
18
0
48
0
6
0
0
% K
% Leu:
18
0
0
0
12
0
48
0
12
18
0
0
6
0
0
% L
% Met:
0
0
6
6
0
0
0
6
0
0
0
0
12
0
30
% M
% Asn:
6
6
18
0
0
0
0
0
18
12
6
42
0
30
0
% N
% Pro:
0
0
0
24
0
48
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
6
0
0
12
0
0
0
0
0
12
% Q
% Arg:
0
0
0
0
0
6
12
0
0
0
0
6
24
0
0
% R
% Ser:
12
0
42
0
0
24
0
18
0
0
0
0
0
12
6
% S
% Thr:
0
6
12
0
0
12
0
36
0
12
0
18
0
0
6
% T
% Val:
0
18
6
48
18
0
6
0
0
0
0
0
12
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
12
0
48
0
0
18
0
0
0
0
0
0
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _