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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDCD5
All Species:
22.73
Human Site:
Y125
Identified Species:
41.67
UniProt:
O14737
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14737
NP_004699.1
125
14285
Y125
D
S
D
E
D
D
D
Y
_
_
_
_
_
_
_
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_533708
138
15446
Y138
D
S
D
E
E
D
D
Y
_
_
_
_
_
_
_
Cat
Felis silvestris
Mouse
Mus musculus
P56812
126
14257
D125
D
S
D
E
D
D
A
D
Y
_
_
_
_
_
_
Rat
Rattus norvegicus
NP_001099717
125
14185
Y125
D
S
D
E
D
D
D
Y
_
_
_
_
_
_
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508827
139
15912
Y139
D
S
D
D
E
D
D
Y
_
_
_
_
_
_
_
Chicken
Gallus gallus
XP_414127
126
14201
Y126
D
S
D
E
E
D
D
Y
_
_
_
_
_
_
_
Frog
Xenopus laevis
NP_001088436
126
14384
Y126
D
S
D
E
D
E
D
Y
_
_
_
_
_
_
_
Zebra Danio
Brachydanio rerio
NP_957471
128
14570
D127
D
S
D
E
E
N
D
D
D
_
_
_
_
_
_
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648848
133
15072
E129
A
I
D
S
D
D
D
E
D
Y
G
C
_
_
_
Honey Bee
Apis mellifera
XP_623981
127
14527
Nematode Worm
Caenorhab. elegans
Q93408
130
14416
D129
L
D
S
D
E
E
L
D
L
_
_
_
_
_
_
Sea Urchin
Strong. purpuratus
XP_783776
128
14619
F128
D
S
D
D
D
D
D
F
_
_
_
_
_
_
_
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001149851
130
14630
R99
S
E
K
V
S
E
E
R
L
I
S
L
L
E
Q
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
77.5
N.A.
95.2
96
N.A.
70.5
84.1
79.3
80.4
N.A.
42.8
51.9
40.7
53.1
Protein Similarity:
100
N.A.
N.A.
79.7
N.A.
96.8
97.5
N.A.
78.4
92
89.6
88.2
N.A.
69.9
71.6
62.3
74.2
P-Site Identity:
100
N.A.
N.A.
87.5
N.A.
66.6
100
N.A.
75
87.5
87.5
55.5
N.A.
33.3
0
0
75
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
77.7
100
N.A.
100
100
100
77.7
N.A.
50
0
33.3
100
Percent
Protein Identity:
N.A.
47.6
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
66.9
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
20
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
70
8
77
24
47
62
70
24
16
0
0
0
0
0
0
% D
% Glu:
0
8
0
54
39
24
8
8
0
0
0
0
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
0
0
0
8
0
0
0
0
0
% I
% Lys:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
8
0
0
0
0
0
8
0
16
0
0
8
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% Q
% Arg:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% R
% Ser:
8
70
8
8
8
0
0
0
0
0
8
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
47
8
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
54
77
77
77
85
85
85
% _