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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAP2K7
All Species:
27.27
Human Site:
Y371
Identified Species:
46.15
UniProt:
O14733
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14733
NP_660186.1
419
47485
Y371
D
H
R
K
R
P
K
Y
N
K
L
L
E
H
S
Chimpanzee
Pan troglodytes
XP_001146898
522
57631
Y474
D
H
R
K
R
P
K
Y
N
K
L
L
E
H
S
Rhesus Macaque
Macaca mulatta
XP_001098659
367
41194
N320
H
R
K
R
P
K
Y
N
K
L
L
E
H
S
F
Dog
Lupus familis
XP_868281
419
47531
Y371
D
H
R
K
R
P
K
Y
N
K
L
L
E
H
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8CE90
535
59294
Y387
D
H
R
K
R
P
K
Y
N
K
L
L
E
H
S
Rat
Rattus norvegicus
Q4KSH7
419
47517
Y371
D
H
R
K
R
P
K
Y
N
K
L
L
E
H
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q07192
446
50082
E399
N
Q
C
L
T
K
D
E
S
K
R
P
K
Y
K
Zebra Danio
Brachydanio rerio
Q9DGE0
361
40575
F314
A
D
R
F
S
A
D
F
V
D
F
T
S
Q
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q23977
1178
125089
Y447
N
H
Q
D
R
P
K
Y
P
E
L
L
A
Q
P
Honey Bee
Apis mellifera
XP_396834
762
86143
Y351
N
Y
K
H
R
P
K
Y
H
K
L
M
E
H
P
Nematode Worm
Caenorhab. elegans
Q20347
363
41178
R316
T
C
L
T
K
D
R
R
H
R
P
K
Y
D
T
Sea Urchin
Strong. purpuratus
XP_795810
281
31449
C234
A
R
T
R
S
A
G
C
A
A
Y
M
A
P
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94A06
354
39192
Q307
E
F
C
S
F
I
S
Q
C
V
Q
K
D
P
R
Baker's Yeast
Sacchar. cerevisiae
P08018
668
72701
Y614
I
P
E
R
R
P
T
Y
A
A
L
T
E
H
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
77
83.5
99
N.A.
77.1
99
N.A.
N.A.
N.A.
40.3
39.3
N.A.
22.4
35.2
34.8
43.6
Protein Similarity:
100
78.1
83.7
99.5
N.A.
77.5
99.5
N.A.
N.A.
N.A.
54.4
56.7
N.A.
27.5
43.3
52
54.4
P-Site Identity:
100
100
6.6
100
N.A.
100
100
N.A.
N.A.
N.A.
6.6
6.6
N.A.
46.6
53.3
0
0
P-Site Similarity:
100
100
20
100
N.A.
100
100
N.A.
N.A.
N.A.
33.3
13.3
N.A.
66.6
86.6
33.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.5
25.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.2
39.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
0
0
0
0
15
0
0
15
15
0
0
15
0
0
% A
% Cys:
0
8
15
0
0
0
0
8
8
0
0
0
0
0
8
% C
% Asp:
36
8
0
8
0
8
15
0
0
8
0
0
8
8
0
% D
% Glu:
8
0
8
0
0
0
0
8
0
8
0
8
50
0
8
% E
% Phe:
0
8
0
8
8
0
0
8
0
0
8
0
0
0
8
% F
% Gly:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% G
% His:
8
43
0
8
0
0
0
0
15
0
0
0
8
50
0
% H
% Ile:
8
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
15
36
8
15
50
0
8
50
0
15
8
0
8
% K
% Leu:
0
0
8
8
0
0
0
0
0
8
65
43
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
15
0
0
0
% M
% Asn:
22
0
0
0
0
0
0
8
36
0
0
0
0
0
0
% N
% Pro:
0
8
0
0
8
58
0
0
8
0
8
8
0
15
22
% P
% Gln:
0
8
8
0
0
0
0
8
0
0
8
0
0
15
0
% Q
% Arg:
0
15
43
22
58
0
8
8
0
8
8
0
0
0
8
% R
% Ser:
0
0
0
8
15
0
8
0
8
0
0
0
8
8
36
% S
% Thr:
8
0
8
8
8
0
8
0
0
0
0
15
0
0
8
% T
% Val:
0
0
0
0
0
0
0
0
8
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
8
58
0
0
8
0
8
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _