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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TRDMT1
All Species:
20
Human Site:
S322
Identified Species:
40
UniProt:
O14717
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14717
NP_004403.1
391
44597
S322
Q
V
E
N
I
Y
K
S
L
T
N
L
S
Q
E
Chimpanzee
Pan troglodytes
XP_001151907
391
44604
S322
Q
V
E
N
I
Y
K
S
L
T
N
L
S
Q
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_848593
391
44814
S322
Q
I
E
D
I
Y
K
S
L
T
N
L
S
Q
E
Cat
Felis silvestris
Mouse
Mus musculus
O55055
415
46776
S322
Q
I
E
N
I
Y
K
S
L
P
D
L
P
P
E
Rat
Rattus norvegicus
Q4G073
391
44051
S322
Q
I
E
N
I
Y
K
S
L
P
D
L
P
P
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520279
343
37945
L281
G
D
L
S
V
E
M
L
R
G
F
L
E
E
D
Chicken
Gallus gallus
NP_001020002
398
45076
H329
E
L
E
S
V
F
K
H
I
E
N
L
T
E
E
Frog
Xenopus laevis
NP_001079673
382
42977
S311
E
I
D
S
V
Y
N
S
L
E
L
L
N
E
E
Zebra Danio
Brachydanio rerio
NP_001018153
381
43910
E317
K
N
L
D
Q
L
S
E
E
D
K
L
K
Q
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001036355
345
39358
Q283
K
S
E
K
I
L
Q
Q
R
L
D
L
L
H
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002309610
350
39899
G288
T
I
Q
P
N
I
K
G
K
E
S
S
L
K
K
Maize
Zea mays
NP_001105173
357
40520
Q295
N
V
P
E
E
K
L
Q
I
S
S
L
K
E
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
N.A.
86.9
N.A.
76.6
81
N.A.
49.3
67
62.1
60.6
N.A.
36
N.A.
N.A.
N.A.
Protein Similarity:
100
100
N.A.
93.6
N.A.
83.8
89.5
N.A.
59.3
80.9
75.4
77.2
N.A.
55.2
N.A.
N.A.
N.A.
P-Site Identity:
100
100
N.A.
86.6
N.A.
66.6
66.6
N.A.
6.6
33.3
33.3
13.3
N.A.
20
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
80
80
N.A.
33.3
86.6
80
26.6
N.A.
46.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
38.1
36.8
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
55.5
56.5
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
6.6
13.3
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
40
40
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
9
17
0
0
0
0
0
9
25
0
0
0
9
% D
% Glu:
17
0
59
9
9
9
0
9
9
25
0
0
9
34
59
% E
% Phe:
0
0
0
0
0
9
0
0
0
0
9
0
0
0
0
% F
% Gly:
9
0
0
0
0
0
0
9
0
9
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
9
0
0
0
0
0
9
0
% H
% Ile:
0
42
0
0
50
9
0
0
17
0
0
0
0
0
0
% I
% Lys:
17
0
0
9
0
9
59
0
9
0
9
0
17
9
9
% K
% Leu:
0
9
17
0
0
17
9
9
50
9
9
92
17
0
17
% L
% Met:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% M
% Asn:
9
9
0
34
9
0
9
0
0
0
34
0
9
0
0
% N
% Pro:
0
0
9
9
0
0
0
0
0
17
0
0
17
17
0
% P
% Gln:
42
0
9
0
9
0
9
17
0
0
0
0
0
34
9
% Q
% Arg:
0
0
0
0
0
0
0
0
17
0
0
0
0
0
0
% R
% Ser:
0
9
0
25
0
0
9
50
0
9
17
9
25
0
0
% S
% Thr:
9
0
0
0
0
0
0
0
0
25
0
0
9
0
0
% T
% Val:
0
25
0
0
25
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
50
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _