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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TRDMT1 All Species: 23.03
Human Site: S153 Identified Species: 46.06
UniProt: O14717 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14717 NP_004403.1 391 44597 S153 E F L L S P T S L G I P N S R
Chimpanzee Pan troglodytes XP_001151907 391 44604 S153 E F L L S P T S L G I P N S R
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_848593 391 44814 S153 E F L L S P T S F G I P N S R
Cat Felis silvestris
Mouse Mus musculus O55055 415 46776 S153 E F L L S P S S L G I P N S R
Rat Rattus norvegicus Q4G073 391 44051 S153 E F L L S P S S L G I P N S R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520279 343 37945 F120 A D G R T N S F L Y L L R I L
Chicken Gallus gallus NP_001020002 398 45076 C153 E F L L S P T C L G I P N S R
Frog Xenopus laevis NP_001079673 382 42977 L150 N S R L R Y F L I A K L Q T E
Zebra Danio Brachydanio rerio NP_001018153 381 43910 S156 E F L I S P T S L G I P N S R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001036355 345 39358 F122 L M E N V K G F E S S Q A R N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002309610 350 39899 T126 V G F E T S D T R A K M I E I
Maize Zea mays NP_001105173 357 40520 Q134 E V S D T H D Q L L E V L S S
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 N.A. 86.9 N.A. 76.6 81 N.A. 49.3 67 62.1 60.6 N.A. 36 N.A. N.A. N.A.
Protein Similarity: 100 100 N.A. 93.6 N.A. 83.8 89.5 N.A. 59.3 80.9 75.4 77.2 N.A. 55.2 N.A. N.A. N.A.
P-Site Identity: 100 100 N.A. 93.3 N.A. 93.3 93.3 N.A. 6.6 93.3 6.6 93.3 N.A. 0 N.A. N.A. N.A.
P-Site Similarity: 100 100 N.A. 93.3 N.A. 100 100 N.A. 26.6 93.3 20 100 N.A. 0 N.A. N.A. N.A.
Percent
Protein Identity: 38.1 36.8 N.A. N.A. N.A. N.A.
Protein Similarity: 55.5 56.5 N.A. N.A. N.A. N.A.
P-Site Identity: 0 20 N.A. N.A. N.A. N.A.
P-Site Similarity: 13.3 26.6 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 0 0 0 0 0 0 0 17 0 0 9 0 0 % A
% Cys: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % C
% Asp: 0 9 0 9 0 0 17 0 0 0 0 0 0 0 0 % D
% Glu: 67 0 9 9 0 0 0 0 9 0 9 0 0 9 9 % E
% Phe: 0 59 9 0 0 0 9 17 9 0 0 0 0 0 0 % F
% Gly: 0 9 9 0 0 0 9 0 0 59 0 0 0 0 0 % G
% His: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 9 0 0 0 0 9 0 59 0 9 9 9 % I
% Lys: 0 0 0 0 0 9 0 0 0 0 17 0 0 0 0 % K
% Leu: 9 0 59 59 0 0 0 9 67 9 9 17 9 0 9 % L
% Met: 0 9 0 0 0 0 0 0 0 0 0 9 0 0 0 % M
% Asn: 9 0 0 9 0 9 0 0 0 0 0 0 59 0 9 % N
% Pro: 0 0 0 0 0 59 0 0 0 0 0 59 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 9 0 0 0 9 9 0 0 % Q
% Arg: 0 0 9 9 9 0 0 0 9 0 0 0 9 9 59 % R
% Ser: 0 9 9 0 59 9 25 50 0 9 9 0 0 67 9 % S
% Thr: 0 0 0 0 25 0 42 9 0 0 0 0 0 9 0 % T
% Val: 9 9 0 0 9 0 0 0 0 0 0 9 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 9 0 0 0 9 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _