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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHD2
All Species:
20.3
Human Site:
Y1278
Identified Species:
34.36
UniProt:
O14647
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14647
NP_001262.3
1828
211344
Y1278
L
G
I
Y
E
H
G
Y
G
N
W
E
L
I
K
Chimpanzee
Pan troglodytes
XP_001170676
1828
211351
Y1278
L
G
I
Y
E
H
G
Y
G
N
W
E
L
I
K
Rhesus Macaque
Macaca mulatta
XP_001097125
1712
197047
V1209
P
T
F
R
I
S
G
V
Q
V
N
A
K
L
V
Dog
Lupus familis
XP_849509
1827
211238
Y1278
L
G
I
Y
E
H
G
Y
G
N
W
E
L
I
K
Cat
Felis silvestris
Mouse
Mus musculus
P40201
1711
196392
N1208
R
I
S
G
V
Q
V
N
A
K
L
V
I
A
H
Rat
Rattus norvegicus
Q9JIX5
2581
290674
Y1642
I
G
V
F
K
H
G
Y
E
K
Y
N
T
M
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513135
1807
208022
Y1271
I
G
I
Y
E
Y
G
Y
G
S
W
E
M
I
K
Chicken
Gallus gallus
Q06A37
3011
338194
F2018
L
E
K
Y
F
N
G
F
V
N
M
C
R
R
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
B0R0I6
2511
279693
Y1686
I
G
V
Y
K
H
G
Y
E
M
Y
T
T
M
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O97159
1982
224182
P1478
E
T
F
A
D
G
V
P
R
E
G
L
S
R
Q
Honey Bee
Apis mellifera
XP_001120496
1675
191695
I1172
G
R
G
P
T
F
K
I
G
G
V
M
V
N
A
Nematode Worm
Caenorhab. elegans
Q22516
1787
205237
N1259
Q
D
W
S
A
Q
N
N
Q
Q
Q
E
E
D
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9S775
1384
158387
K882
G
K
R
K
R
S
R
K
Q
L
V
S
I
E
E
Baker's Yeast
Sacchar. cerevisiae
P32657
1468
168223
R966
E
Q
L
E
M
M
N
R
R
D
N
A
L
K
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
58.1
98.4
N.A.
57.1
23.3
N.A.
58.5
22.1
N.A.
22.2
N.A.
27.6
50
28.3
N.A.
Protein Similarity:
100
99.9
71.1
99.3
N.A.
70.4
39.6
N.A.
72.7
36.4
N.A.
39
N.A.
45.6
64.7
48.1
N.A.
P-Site Identity:
100
100
6.6
100
N.A.
0
26.6
N.A.
73.3
26.6
N.A.
33.3
N.A.
0
6.6
6.6
N.A.
P-Site Similarity:
100
100
13.3
100
N.A.
6.6
73.3
N.A.
100
40
N.A.
73.3
N.A.
13.3
13.3
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.9
31.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.7
48.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
8
0
0
0
8
0
0
15
0
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
8
0
0
8
0
0
0
0
8
0
0
0
8
8
% D
% Glu:
15
8
0
8
29
0
0
0
15
8
0
36
8
8
8
% E
% Phe:
0
0
15
8
8
8
0
8
0
0
0
0
0
0
0
% F
% Gly:
15
43
8
8
0
8
58
0
36
8
8
0
0
0
0
% G
% His:
0
0
0
0
0
36
0
0
0
0
0
0
0
0
8
% H
% Ile:
22
8
29
0
8
0
0
8
0
0
0
0
15
29
0
% I
% Lys:
0
8
8
8
15
0
8
8
0
15
0
0
8
8
36
% K
% Leu:
29
0
8
0
0
0
0
0
0
8
8
8
29
8
0
% L
% Met:
0
0
0
0
8
8
0
0
0
8
8
8
8
15
0
% M
% Asn:
0
0
0
0
0
8
15
15
0
29
15
8
0
8
0
% N
% Pro:
8
0
0
8
0
0
0
8
0
0
0
0
0
0
0
% P
% Gln:
8
8
0
0
0
15
0
0
22
8
8
0
0
0
8
% Q
% Arg:
8
8
8
8
8
0
8
8
15
0
0
0
8
15
15
% R
% Ser:
0
0
8
8
0
15
0
0
0
8
0
8
8
0
0
% S
% Thr:
0
15
0
0
8
0
0
0
0
0
0
8
15
0
0
% T
% Val:
0
0
15
0
8
0
15
8
8
8
15
8
8
0
15
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
29
0
0
0
0
% W
% Tyr:
0
0
0
43
0
8
0
43
0
0
15
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _