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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHD2
All Species:
10.91
Human Site:
T1249
Identified Species:
18.46
UniProt:
O14647
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14647
NP_001262.3
1828
211344
T1249
E
K
K
K
Y
C
L
T
C
R
V
K
A
A
H
Chimpanzee
Pan troglodytes
XP_001170676
1828
211351
T1249
E
K
K
K
Y
C
L
T
C
R
V
K
A
A
H
Rhesus Macaque
Macaca mulatta
XP_001097125
1712
197047
K1183
N
G
C
I
K
A
L
K
D
S
S
S
G
T
E
Dog
Lupus familis
XP_849509
1827
211238
T1249
E
K
K
K
Y
C
L
T
C
R
V
K
A
A
H
Cat
Felis silvestris
Mouse
Mus musculus
P40201
1711
196392
S1182
V
K
A
L
K
D
S
S
S
G
T
E
R
A
G
Rat
Rattus norvegicus
Q9JIX5
2581
290674
A1596
Q
E
V
I
G
D
Q
A
E
K
V
L
G
G
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513135
1807
208022
P1242
E
R
K
R
Y
T
I
P
C
H
T
K
A
A
H
Chicken
Gallus gallus
Q06A37
3011
338194
F1985
V
S
T
F
G
I
I
F
D
P
I
K
H
Q
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
B0R0I6
2511
279693
H1639
K
Q
E
V
I
G
E
H
A
D
S
V
L
S
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O97159
1982
224182
K1452
G
K
S
E
R
N
F
K
A
Y
V
S
L
F
M
Honey Bee
Apis mellifera
XP_001120496
1675
191695
S1146
T
C
L
S
E
F
E
S
T
A
K
E
N
K
G
Nematode Worm
Caenorhab. elegans
Q22516
1787
205237
E1229
Y
E
Q
D
Q
E
T
E
L
Q
K
L
G
K
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9S775
1384
158387
E856
S
D
R
A
S
Y
W
E
E
L
L
K
D
K
F
Baker's Yeast
Sacchar. cerevisiae
P32657
1468
168223
E940
D
D
I
I
P
E
E
E
L
K
K
L
Q
D
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
58.1
98.4
N.A.
57.1
23.3
N.A.
58.5
22.1
N.A.
22.2
N.A.
27.6
50
28.3
N.A.
Protein Similarity:
100
99.9
71.1
99.3
N.A.
70.4
39.6
N.A.
72.7
36.4
N.A.
39
N.A.
45.6
64.7
48.1
N.A.
P-Site Identity:
100
100
6.6
100
N.A.
13.3
6.6
N.A.
53.3
6.6
N.A.
0
N.A.
13.3
0
0
N.A.
P-Site Similarity:
100
100
6.6
100
N.A.
26.6
26.6
N.A.
73.3
20
N.A.
26.6
N.A.
20
13.3
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.9
31.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.7
48.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
0
8
0
8
15
8
0
0
29
36
8
% A
% Cys:
0
8
8
0
0
22
0
0
29
0
0
0
0
0
0
% C
% Asp:
8
15
0
8
0
15
0
0
15
8
0
0
8
8
0
% D
% Glu:
29
15
8
8
8
15
22
22
15
0
0
15
0
0
15
% E
% Phe:
0
0
0
8
0
8
8
8
0
0
0
0
0
8
15
% F
% Gly:
8
8
0
0
15
8
0
0
0
8
0
0
22
8
29
% G
% His:
0
0
0
0
0
0
0
8
0
8
0
0
8
0
29
% H
% Ile:
0
0
8
22
8
8
15
0
0
0
8
0
0
0
0
% I
% Lys:
8
36
29
22
15
0
0
15
0
15
22
43
0
22
0
% K
% Leu:
0
0
8
8
0
0
29
0
15
8
8
22
15
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
8
0
0
0
0
8
0
0
0
0
0
0
8
0
0
% N
% Pro:
0
0
0
0
8
0
0
8
0
8
0
0
0
0
0
% P
% Gln:
8
8
8
0
8
0
8
0
0
8
0
0
8
8
0
% Q
% Arg:
0
8
8
8
8
0
0
0
0
22
0
0
8
0
0
% R
% Ser:
8
8
8
8
8
0
8
15
8
8
15
15
0
8
0
% S
% Thr:
8
0
8
0
0
8
8
22
8
0
15
0
0
8
0
% T
% Val:
15
0
8
8
0
0
0
0
0
0
36
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
29
8
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _