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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHD2
All Species:
21.52
Human Site:
S450
Identified Species:
36.41
UniProt:
O14647
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14647
NP_001262.3
1828
211344
S450
S
F
H
S
R
N
N
S
K
T
I
P
T
R
E
Chimpanzee
Pan troglodytes
XP_001170676
1828
211351
S450
S
F
H
S
R
N
N
S
K
T
I
P
T
R
E
Rhesus Macaque
Macaca mulatta
XP_001097125
1712
197047
S448
E
Y
F
S
R
N
Q
S
K
T
T
P
F
K
D
Dog
Lupus familis
XP_849509
1827
211238
S450
S
F
H
S
R
N
N
S
K
T
I
P
T
R
E
Cat
Felis silvestris
Mouse
Mus musculus
P40201
1711
196392
S444
E
Y
F
S
R
N
Q
S
K
T
T
P
F
K
D
Rat
Rattus norvegicus
Q9JIX5
2581
290674
V767
T
W
E
L
K
E
D
V
D
E
G
K
I
R
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513135
1807
208022
S447
E
Y
F
S
R
N
Q
S
K
T
T
P
F
K
D
Chicken
Gallus gallus
Q06A37
3011
338194
E940
F
E
K
L
M
S
R
E
P
E
M
E
R
V
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
B0R0I6
2511
279693
N710
E
F
F
V
K
Y
K
N
Y
S
Y
M
H
C
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O97159
1982
224182
V690
G
R
K
S
K
L
K
V
E
D
D
E
D
R
P
Honey Bee
Apis mellifera
XP_001120496
1675
191695
G433
P
K
F
H
Q
L
K
G
Q
P
D
Y
M
G
K
Nematode Worm
Caenorhab. elegans
Q22516
1787
205237
S464
M
Y
W
R
K
V
D
S
E
N
P
P
I
F
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9S775
1384
158387
Y155
E
K
E
F
Q
K
A
Y
K
S
N
H
R
L
K
Baker's Yeast
Sacchar. cerevisiae
P32657
1468
168223
L239
S
I
G
Q
V
R
G
L
K
R
L
D
N
Y
C
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
58.1
98.4
N.A.
57.1
23.3
N.A.
58.5
22.1
N.A.
22.2
N.A.
27.6
50
28.3
N.A.
Protein Similarity:
100
99.9
71.1
99.3
N.A.
70.4
39.6
N.A.
72.7
36.4
N.A.
39
N.A.
45.6
64.7
48.1
N.A.
P-Site Identity:
100
100
46.6
100
N.A.
46.6
13.3
N.A.
46.6
6.6
N.A.
13.3
N.A.
13.3
0
20
N.A.
P-Site Similarity:
100
100
66.6
100
N.A.
66.6
40
N.A.
66.6
20
N.A.
33.3
N.A.
26.6
20
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.9
31.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.7
48.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% C
% Asp:
0
0
0
0
0
0
15
0
8
8
15
8
8
0
22
% D
% Glu:
36
8
15
0
0
8
0
8
15
15
0
15
0
0
50
% E
% Phe:
8
29
36
8
0
0
0
0
0
0
0
0
22
8
0
% F
% Gly:
8
0
8
0
0
0
8
8
0
0
8
0
0
8
0
% G
% His:
0
0
22
8
0
0
0
0
0
0
0
8
8
0
0
% H
% Ile:
0
8
0
0
0
0
0
0
0
0
22
0
15
0
0
% I
% Lys:
0
15
15
0
29
8
22
0
58
0
0
8
0
22
15
% K
% Leu:
0
0
0
15
0
15
0
8
0
0
8
0
0
8
0
% L
% Met:
8
0
0
0
8
0
0
0
0
0
8
8
8
0
0
% M
% Asn:
0
0
0
0
0
43
22
8
0
8
8
0
8
0
0
% N
% Pro:
8
0
0
0
0
0
0
0
8
8
8
50
0
0
8
% P
% Gln:
0
0
0
8
15
0
22
0
8
0
0
0
0
0
0
% Q
% Arg:
0
8
0
8
43
8
8
0
0
8
0
0
15
36
0
% R
% Ser:
29
0
0
50
0
8
0
50
0
15
0
0
0
0
0
% S
% Thr:
8
0
0
0
0
0
0
0
0
43
22
0
22
0
0
% T
% Val:
0
0
0
8
8
8
0
15
0
0
0
0
0
8
0
% V
% Trp:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
29
0
0
0
8
0
8
8
0
8
8
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _