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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDX4
All Species:
16.06
Human Site:
S74
Identified Species:
32.12
UniProt:
O14627
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14627
NP_005184.1
284
30480
S74
P
S
L
G
V
W
G
S
P
Y
S
P
P
R
E
Chimpanzee
Pan troglodytes
XP_529040
263
28214
H65
H
M
P
S
M
D
P
H
W
P
S
L
G
V
W
Rhesus Macaque
Macaca mulatta
XP_001095271
284
30475
S74
Q
S
L
G
D
W
G
S
P
Y
S
P
P
R
E
Dog
Lupus familis
XP_549080
326
35316
S116
P
S
L
G
V
W
G
S
P
Y
S
P
S
R
E
Cat
Felis silvestris
Mouse
Mus musculus
Q07424
282
30447
S74
P
S
L
G
A
W
S
S
P
Y
S
P
P
R
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519363
116
13475
Chicken
Gallus gallus
Q9DEB6
260
28826
W62
H
G
Q
P
A
A
A
W
G
S
P
Y
T
P
A
Frog
Xenopus laevis
Q91622
263
29182
Y65
P
G
G
T
W
S
S
Y
T
P
S
R
E
D
W
Zebra Danio
Brachydanio rerio
Q9PWM5
227
26341
T29
P
S
V
A
I
S
S
T
N
Y
D
P
V
R
H
Tiger Blowfish
Takifugu rubipres
O13074
288
32704
G74
Y
T
Q
C
Q
R
A
G
Q
P
A
S
V
V
M
Fruit Fly
Dros. melanogaster
P09085
427
45708
I174
P
P
N
H
Q
Q
H
I
A
E
G
L
P
S
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P13545
308
33276
S91
T
A
G
Y
G
D
H
S
T
T
S
A
G
Y
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.1
93.6
69.9
N.A.
82.7
N.A.
N.A.
33.7
39.4
38.7
26.4
27.7
28.1
N.A.
N.A.
24.3
Protein Similarity:
100
90.8
94.7
75.1
N.A.
87.6
N.A.
N.A.
36.2
54.2
50.3
41.2
39.5
38.1
N.A.
N.A.
39.6
P-Site Identity:
100
6.6
86.6
93.3
N.A.
86.6
N.A.
N.A.
0
0
13.3
33.3
0
13.3
N.A.
N.A.
13.3
P-Site Similarity:
100
13.3
86.6
93.3
N.A.
86.6
N.A.
N.A.
0
0
13.3
53.3
13.3
13.3
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
9
17
9
17
0
9
0
9
9
0
0
9
% A
% Cys:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
9
17
0
0
0
0
9
0
0
9
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
9
0
0
9
0
34
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
17
17
34
9
0
25
9
9
0
9
0
17
0
9
% G
% His:
17
0
0
9
0
0
17
9
0
0
0
0
0
0
9
% H
% Ile:
0
0
0
0
9
0
0
9
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
34
0
0
0
0
0
0
0
0
17
0
0
0
% L
% Met:
0
9
0
0
9
0
0
0
0
0
0
0
0
0
9
% M
% Asn:
0
0
9
0
0
0
0
0
9
0
0
0
0
0
0
% N
% Pro:
50
9
9
9
0
0
9
0
34
25
9
42
34
9
9
% P
% Gln:
9
0
17
0
17
9
0
0
9
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
9
0
0
0
0
0
9
0
42
0
% R
% Ser:
0
42
0
9
0
17
25
42
0
9
59
9
9
9
0
% S
% Thr:
9
9
0
9
0
0
0
9
17
9
0
0
9
0
0
% T
% Val:
0
0
9
0
17
0
0
0
0
0
0
0
17
17
0
% V
% Trp:
0
0
0
0
9
34
0
9
9
0
0
0
0
0
17
% W
% Tyr:
9
0
0
9
0
0
0
9
0
42
0
9
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _