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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDX4
All Species:
14.85
Human Site:
S250
Identified Species:
29.7
UniProt:
O14627
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14627
NP_005184.1
284
30480
S250
G
G
S
V
Q
S
D
S
D
S
I
S
P
G
E
Chimpanzee
Pan troglodytes
XP_529040
263
28214
S231
S
V
Q
S
D
S
D
S
I
S
P
G
E
L
P
Rhesus Macaque
Macaca mulatta
XP_001095271
284
30475
S250
G
G
S
V
Q
S
D
S
G
S
I
S
P
G
E
Dog
Lupus familis
XP_549080
326
35316
S292
G
S
S
V
Q
S
D
S
G
S
I
S
P
G
E
Cat
Felis silvestris
Mouse
Mus musculus
Q07424
282
30447
S248
G
G
S
V
Q
S
D
S
G
S
I
S
P
G
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519363
116
13475
S84
S
A
Q
S
D
S
G
S
V
S
P
A
E
L
P
Chicken
Gallus gallus
Q9DEB6
260
28826
A228
T
T
T
P
T
P
P
A
V
G
T
P
G
P
M
Frog
Xenopus laevis
Q91622
263
29182
G231
T
P
T
P
P
S
V
G
T
T
A
G
M
G
G
Zebra Danio
Brachydanio rerio
Q9PWM5
227
26341
N195
M
K
W
K
K
E
S
N
L
T
S
I
L
N
D
Tiger Blowfish
Takifugu rubipres
O13074
288
32704
K243
Q
V
L
T
G
F
P
K
P
H
W
T
P
I
A
Fruit Fly
Dros. melanogaster
P09085
427
45708
M374
S
H
S
L
A
H
S
M
N
P
M
A
A
M
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P13545
308
33276
N264
S
G
E
G
E
G
E
N
E
S
E
S
T
G
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.1
93.6
69.9
N.A.
82.7
N.A.
N.A.
33.7
39.4
38.7
26.4
27.7
28.1
N.A.
N.A.
24.3
Protein Similarity:
100
90.8
94.7
75.1
N.A.
87.6
N.A.
N.A.
36.2
54.2
50.3
41.2
39.5
38.1
N.A.
N.A.
39.6
P-Site Identity:
100
26.6
93.3
86.6
N.A.
93.3
N.A.
N.A.
20
0
13.3
0
6.6
6.6
N.A.
N.A.
26.6
P-Site Similarity:
100
26.6
93.3
86.6
N.A.
93.3
N.A.
N.A.
26.6
13.3
26.6
26.6
13.3
33.3
N.A.
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
9
0
0
9
0
0
9
17
9
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
17
0
42
0
9
0
0
0
0
0
9
% D
% Glu:
0
0
9
0
9
9
9
0
9
0
9
0
17
0
34
% E
% Phe:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% F
% Gly:
34
34
0
9
9
9
9
9
25
9
0
17
9
50
9
% G
% His:
0
9
0
0
0
9
0
0
0
9
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
9
0
34
9
0
9
0
% I
% Lys:
0
9
0
9
9
0
0
9
0
0
0
0
0
0
0
% K
% Leu:
0
0
9
9
0
0
0
0
9
0
0
0
9
17
0
% L
% Met:
9
0
0
0
0
0
0
9
0
0
9
0
9
9
9
% M
% Asn:
0
0
0
0
0
0
0
17
9
0
0
0
0
9
9
% N
% Pro:
0
9
0
17
9
9
17
0
9
9
17
9
42
9
17
% P
% Gln:
9
0
17
0
34
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
34
9
42
17
0
59
17
50
0
59
9
42
0
0
0
% S
% Thr:
17
9
17
9
9
0
0
0
9
17
9
9
9
0
9
% T
% Val:
0
17
0
34
0
0
9
0
17
0
0
0
0
0
0
% V
% Trp:
0
0
9
0
0
0
0
0
0
0
9
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _