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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CIT All Species: 16.36
Human Site: S386 Identified Species: 40
UniProt: O14578 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14578 NP_009105.1 2027 231431 S386 L K S D D D T S N F D E P E K
Chimpanzee Pan troglodytes XP_001158928 2027 231356 S386 L K S D D D T S N F D E P E K
Rhesus Macaque Macaca mulatta XP_001085560 2069 236690 S386 L K S D D D T S N F D E P E K
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus P49025 2055 235371 S385 L K S D D D T S N F D E P E K
Rat Rattus norvegicus Q7TT49 1713 194869 G256 Q A M E D G M G K Y G P E C D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513915 588 68657
Chicken Gallus gallus XP_415277 2027 231609 T385 T L K S D D D T S N F D E P E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001919786 1119 126974
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W1B0 1637 186706 Y180 L Y L V M D Y Y C G G D L L T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001199576 1369 153558
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 97.6 N.A. N.A. 94.5 24.2 N.A. 23.6 90.2 N.A. 35.9 N.A. 23.1 N.A. N.A. 26.4
Protein Similarity: 100 99.9 97.7 N.A. N.A. 96.5 42.3 N.A. 26.7 95.9 N.A. 45.4 N.A. 41.4 N.A. N.A. 41.5
P-Site Identity: 100 100 100 N.A. N.A. 100 6.6 N.A. 0 13.3 N.A. 0 N.A. 13.3 N.A. N.A. 0
P-Site Similarity: 100 100 100 N.A. N.A. 100 20 N.A. 0 40 N.A. 0 N.A. 20 N.A. N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 10 0 0 0 0 10 0 % C
% Asp: 0 0 0 40 60 60 10 0 0 0 40 20 0 0 10 % D
% Glu: 0 0 0 10 0 0 0 0 0 0 0 40 20 40 10 % E
% Phe: 0 0 0 0 0 0 0 0 0 40 10 0 0 0 0 % F
% Gly: 0 0 0 0 0 10 0 10 0 10 20 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 40 10 0 0 0 0 0 10 0 0 0 0 0 40 % K
% Leu: 50 10 10 0 0 0 0 0 0 0 0 0 10 10 0 % L
% Met: 0 0 10 0 10 0 10 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 40 10 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 10 40 10 0 % P
% Gln: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 40 10 0 0 0 40 10 0 0 0 0 0 0 % S
% Thr: 10 0 0 0 0 0 40 10 0 0 0 0 0 0 10 % T
% Val: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 0 0 0 0 10 10 0 10 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _