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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM194A
All Species:
26.06
Human Site:
Y268
Identified Species:
57.33
UniProt:
O14524
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14524
NP_001124435.1
444
50640
Y268
S
F
A
V
C
Y
K
Y
G
P
L
E
N
E
R
Chimpanzee
Pan troglodytes
XP_509153
534
60335
Y358
S
F
A
V
C
Y
K
Y
G
P
L
E
N
E
R
Rhesus Macaque
Macaca mulatta
XP_001099369
483
55744
Y307
S
F
A
V
C
Y
K
Y
G
P
L
E
N
E
R
Dog
Lupus familis
XP_849067
482
55163
Y307
S
F
A
I
C
Y
K
Y
G
P
L
E
N
E
R
Cat
Felis silvestris
Mouse
Mus musculus
Q6ZQE4
437
49798
Y266
S
F
A
V
C
Y
K
Y
G
P
L
E
N
E
R
Rat
Rattus norvegicus
P0C8N6
421
47662
L249
G
Y
V
L
V
V
G
L
C
S
F
S
A
C
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506304
296
32534
L127
S
P
L
Y
V
I
L
L
G
G
W
S
F
S
L
Chicken
Gallus gallus
Q5ZJY9
447
50997
H255
S
F
A
T
C
Y
Q
H
G
P
L
T
S
E
L
Frog
Xenopus laevis
A1L3G9
434
50308
Y258
S
F
A
F
C
Y
I
Y
G
P
L
E
N
E
R
Zebra Danio
Brachydanio rerio
XP_683418
446
51761
Y261
S
F
A
V
C
Y
R
Y
G
P
L
V
E
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001196379
590
65450
R396
A
L
V
G
F
F
M
R
W
I
V
E
N
Y
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
82.7
89.2
80.9
N.A.
82.6
33.3
N.A.
31.3
36.9
59
50.9
N.A.
N.A.
N.A.
N.A.
25.7
Protein Similarity:
100
83.1
90.4
84.8
N.A.
90
52
N.A.
41.6
55
74.7
69
N.A.
N.A.
N.A.
N.A.
45.9
P-Site Identity:
100
100
100
93.3
N.A.
100
0
N.A.
13.3
60
86.6
80
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
13.3
N.A.
13.3
80
86.6
86.6
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
73
0
0
0
0
0
0
0
0
0
10
0
0
% A
% Cys:
0
0
0
0
73
0
0
0
10
0
0
0
0
10
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
64
10
73
0
% E
% Phe:
0
73
0
10
10
10
0
0
0
0
10
0
10
0
0
% F
% Gly:
10
0
0
10
0
0
10
0
82
10
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
0
10
10
0
0
10
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
46
0
0
0
0
0
0
0
0
% K
% Leu:
0
10
10
10
0
0
10
19
0
0
73
0
0
0
28
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
64
0
0
% N
% Pro:
0
10
0
0
0
0
0
0
0
73
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
10
10
0
0
0
0
0
0
64
% R
% Ser:
82
0
0
0
0
0
0
0
0
10
0
19
10
10
0
% S
% Thr:
0
0
0
10
0
0
0
0
0
0
0
10
0
0
0
% T
% Val:
0
0
19
46
19
10
0
0
0
0
10
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
10
0
10
0
0
0
0
% W
% Tyr:
0
10
0
10
0
73
0
64
0
0
0
0
0
10
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _