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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM194A
All Species:
20
Human Site:
S424
Identified Species:
44
UniProt:
O14524
Number Species:
10
Phosphosite Substitution
Charge Score:
0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14524
NP_001124435.1
444
50640
S424
D
E
I
Y
E
E
A
S
S
E
E
E
D
S
Y
Chimpanzee
Pan troglodytes
XP_509153
534
60335
S514
D
E
I
Y
E
E
A
S
S
E
E
E
D
S
Y
Rhesus Macaque
Macaca mulatta
XP_001099369
483
55744
S463
D
E
I
Y
E
E
A
S
S
E
E
E
D
S
Y
Dog
Lupus familis
XP_849067
482
55163
S463
D
E
I
Y
E
E
T
S
T
E
E
E
D
S
D
Cat
Felis silvestris
Mouse
Mus musculus
Q6ZQE4
437
49798
E417
S
I
F
T
Q
D
E
E
L
S
S
E
E
E
G
Rat
Rattus norvegicus
P0C8N6
421
47662
G400
S
T
H
E
K
Q
Y
G
L
G
G
A
F
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506304
296
32534
E277
D
F
S
I
E
D
D
E
P
L
E
P
L
E
P
Chicken
Gallus gallus
Q5ZJY9
447
50997
T412
E
Q
L
F
E
T
R
T
E
S
E
Q
D
E
T
Frog
Xenopus laevis
A1L3G9
434
50308
S414
D
E
L
F
G
E
D
S
D
V
E
E
E
M
E
Zebra Danio
Brachydanio rerio
XP_683418
446
51761
E415
D
E
L
F
S
T
D
E
E
D
K
E
E
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001196379
590
65450
T566
D
F
Y
A
S
D
V
T
L
I
S
E
D
D
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
82.7
89.2
80.9
N.A.
82.6
33.3
N.A.
31.3
36.9
59
50.9
N.A.
N.A.
N.A.
N.A.
25.7
Protein Similarity:
100
83.1
90.4
84.8
N.A.
90
52
N.A.
41.6
55
74.7
69
N.A.
N.A.
N.A.
N.A.
45.9
P-Site Identity:
100
100
100
80
N.A.
6.6
0
N.A.
20
20
40
20
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
100
100
86.6
N.A.
26.6
13.3
N.A.
26.6
60
60
53.3
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
28
0
0
0
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
73
0
0
0
0
28
28
0
10
10
0
0
55
10
10
% D
% Glu:
10
55
0
10
55
46
10
28
19
37
64
73
28
37
28
% E
% Phe:
0
19
10
28
0
0
0
0
0
0
0
0
10
0
0
% F
% Gly:
0
0
0
0
10
0
0
10
0
10
10
0
0
0
10
% G
% His:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
37
10
0
0
0
0
0
10
0
0
0
0
0
% I
% Lys:
0
0
0
0
10
0
0
0
0
0
10
0
0
0
0
% K
% Leu:
0
0
28
0
0
0
0
0
28
10
0
0
10
10
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
10
0
0
10
0
0
10
% P
% Gln:
0
10
0
0
10
10
0
0
0
0
0
10
0
0
0
% Q
% Arg:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% R
% Ser:
19
0
10
0
19
0
0
46
28
19
19
0
0
37
0
% S
% Thr:
0
10
0
10
0
19
10
19
10
0
0
0
0
0
10
% T
% Val:
0
0
0
0
0
0
10
0
0
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
37
0
0
10
0
0
0
0
0
0
0
28
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _