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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM194A
All Species:
19.7
Human Site:
S118
Identified Species:
43.33
UniProt:
O14524
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14524
NP_001124435.1
444
50640
S118
S
I
W
N
F
F
S
S
F
L
K
E
K
L
N
Chimpanzee
Pan troglodytes
XP_509153
534
60335
S208
S
I
W
N
F
F
S
S
F
L
K
E
K
L
N
Rhesus Macaque
Macaca mulatta
XP_001099369
483
55744
S157
S
I
W
N
F
F
S
S
F
L
K
E
K
L
N
Dog
Lupus familis
XP_849067
482
55163
S157
S
I
W
N
F
F
S
S
F
L
K
E
K
L
N
Cat
Felis silvestris
Mouse
Mus musculus
Q6ZQE4
437
49798
S116
S
I
W
N
F
F
S
S
F
L
K
E
K
L
N
Rat
Rattus norvegicus
P0C8N6
421
47662
K114
F
W
T
A
E
E
A
K
E
V
T
I
V
F
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506304
296
32534
Chicken
Gallus gallus
Q5ZJY9
447
50997
T114
R
P
E
T
S
T
E
T
F
L
K
I
K
Q
Y
Frog
Xenopus laevis
A1L3G9
434
50308
D116
F
L
K
E
K
L
N
D
T
F
I
Y
V
N
L
Zebra Danio
Brachydanio rerio
XP_683418
446
51761
E119
F
V
R
E
Q
T
N
E
T
T
I
S
V
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001196379
590
65450
H228
S
N
E
S
A
G
F
H
I
Y
C
H
S
G
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
82.7
89.2
80.9
N.A.
82.6
33.3
N.A.
31.3
36.9
59
50.9
N.A.
N.A.
N.A.
N.A.
25.7
Protein Similarity:
100
83.1
90.4
84.8
N.A.
90
52
N.A.
41.6
55
74.7
69
N.A.
N.A.
N.A.
N.A.
45.9
P-Site Identity:
100
100
100
100
N.A.
100
0
N.A.
0
26.6
0
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
20
N.A.
0
33.3
13.3
13.3
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
10
0
10
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% D
% Glu:
0
0
19
19
10
10
10
10
10
0
0
46
0
0
0
% E
% Phe:
28
0
0
0
46
46
10
0
55
10
0
0
0
10
0
% F
% Gly:
0
0
0
0
0
10
0
0
0
0
0
0
0
10
0
% G
% His:
0
0
0
0
0
0
0
10
0
0
0
10
0
0
0
% H
% Ile:
0
46
0
0
0
0
0
0
10
0
19
19
0
0
0
% I
% Lys:
0
0
10
0
10
0
0
10
0
0
55
0
55
0
0
% K
% Leu:
0
10
0
0
0
10
0
0
0
55
0
0
0
46
19
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
46
0
0
19
0
0
0
0
0
0
10
46
% N
% Pro:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
10
0
0
0
0
0
0
0
0
10
0
% Q
% Arg:
10
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
55
0
0
10
10
0
46
46
0
0
0
10
10
10
19
% S
% Thr:
0
0
10
10
0
19
0
10
19
10
10
0
0
0
0
% T
% Val:
0
10
0
0
0
0
0
0
0
10
0
0
28
0
0
% V
% Trp:
0
10
46
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
10
0
10
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _