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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C2CD2L
All Species:
24.85
Human Site:
S421
Identified Species:
68.33
UniProt:
O14523
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14523
NP_055622.3
706
76181
S421
N
L
G
T
P
T
S
S
T
P
R
P
S
I
T
Chimpanzee
Pan troglodytes
XP_508807
706
76194
S421
N
L
G
T
P
T
S
S
T
P
R
P
S
I
T
Rhesus Macaque
Macaca mulatta
XP_001102496
707
76118
S421
N
L
G
T
P
T
S
S
T
P
R
P
S
I
T
Dog
Lupus familis
XP_853252
707
75832
S421
N
L
G
T
P
T
P
S
T
P
R
P
S
I
T
Cat
Felis silvestris
Mouse
Mus musculus
Q80X80
706
76339
S421
N
L
G
T
P
T
S
S
T
P
R
P
S
I
T
Rat
Rattus norvegicus
NP_001011996
706
76042
S421
N
L
G
T
P
T
S
S
T
P
R
P
S
I
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511393
810
87628
P512
K
S
W
Q
G
P
F
P
I
P
A
A
K
V
E
Chicken
Gallus gallus
XP_425792
680
73242
T389
S
L
N
A
Q
H
A
T
S
L
H
T
S
I
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001070851
708
76492
E410
P
T
A
I
V
S
L
E
L
A
Y
V
E
S
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98
92.7
N.A.
90.7
91.2
N.A.
29.1
61.3
N.A.
52.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
98.8
95.9
N.A.
94.1
94.3
N.A.
45.9
72.9
N.A.
69
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
100
100
N.A.
6.6
26.6
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
13.3
53.3
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
12
12
0
0
12
0
0
12
12
12
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
12
0
0
0
0
12
0
12
% E
% Phe:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
67
0
12
0
0
0
0
0
0
0
0
0
12
% G
% His:
0
0
0
0
0
12
0
0
0
0
12
0
0
0
0
% H
% Ile:
0
0
0
12
0
0
0
0
12
0
0
0
0
78
0
% I
% Lys:
12
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% K
% Leu:
0
78
0
0
0
0
12
0
12
12
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
67
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
12
0
0
0
67
12
12
12
0
78
0
67
0
0
0
% P
% Gln:
0
0
0
12
12
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
67
0
0
0
0
% R
% Ser:
12
12
0
0
0
12
56
67
12
0
0
0
78
12
0
% S
% Thr:
0
12
0
67
0
67
0
12
67
0
0
12
0
0
78
% T
% Val:
0
0
0
0
12
0
0
0
0
0
0
12
0
12
0
% V
% Trp:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _