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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SOCS2
All Species:
26.97
Human Site:
Y190
Identified Species:
59.33
UniProt:
O14508
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14508
NP_003868.1
198
22172
Y190
L
P
T
R
L
K
D
Y
L
E
E
Y
K
F
Q
Chimpanzee
Pan troglodytes
XP_001139731
243
27147
Y190
L
P
T
R
L
K
D
Y
L
E
E
Y
K
F
Q
Rhesus Macaque
Macaca mulatta
XP_001097728
264
29346
Q230
R
S
S
A
R
S
L
Q
H
L
C
R
L
V
I
Dog
Lupus familis
XP_539720
198
22236
Y190
L
P
T
R
L
K
D
Y
L
E
E
Y
K
F
Q
Cat
Felis silvestris
Mouse
Mus musculus
O35717
198
22415
Y190
L
P
T
R
L
K
D
Y
L
E
E
Y
K
F
Q
Rat
Rattus norvegicus
O88582
198
22361
Y190
L
P
T
R
L
K
D
Y
L
E
E
Y
K
F
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511644
191
21779
L184
P
T
R
L
K
D
Y
L
K
E
Y
Q
Y
Q
V
Chicken
Gallus gallus
Q9PW70
249
28100
T226
R
L
R
I
N
R
C
T
T
E
V
E
R
L
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001108022
197
22308
Y189
L
P
N
R
L
K
D
Y
L
T
D
Y
T
Y
N
Tiger Blowfish
Takifugu rubipres
NP_001116332
201
22377
Y193
L
P
G
R
L
K
D
Y
L
T
E
Y
S
Y
H
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_799032
227
25956
T197
L
Q
H
L
C
R
C
T
V
N
K
T
V
E
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80.6
39
94.4
N.A.
93.9
93.4
N.A.
79.8
41.7
N.A.
57
53.2
N.A.
N.A.
N.A.
37.4
Protein Similarity:
100
81.4
51.5
95.9
N.A.
95.4
95.9
N.A.
87.3
51.4
N.A.
71.7
69.6
N.A.
N.A.
N.A.
50.2
P-Site Identity:
100
100
0
100
N.A.
100
100
N.A.
6.6
6.6
N.A.
60
66.6
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
6.6
100
N.A.
100
100
N.A.
6.6
20
N.A.
73.3
73.3
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
10
0
19
0
0
0
10
0
0
0
0
% C
% Asp:
0
0
0
0
0
10
64
0
0
0
10
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
64
55
10
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
46
0
% F
% Gly:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
10
0
0
0
0
0
10
0
0
0
0
0
10
% H
% Ile:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
10
% I
% Lys:
0
0
0
0
10
64
0
0
10
0
10
0
46
0
0
% K
% Leu:
73
10
0
19
64
0
10
10
64
10
0
0
10
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
10
0
0
0
0
10
0
0
0
0
10
% N
% Pro:
10
64
0
0
0
0
0
0
0
0
0
0
0
0
19
% P
% Gln:
0
10
0
0
0
0
0
10
0
0
0
10
0
10
46
% Q
% Arg:
19
0
19
64
10
19
0
0
0
0
0
10
10
0
0
% R
% Ser:
0
10
10
0
0
10
0
0
0
0
0
0
10
0
0
% S
% Thr:
0
10
46
0
0
0
0
19
10
19
0
10
10
0
0
% T
% Val:
0
0
0
0
0
0
0
0
10
0
10
0
10
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
64
0
0
10
64
10
19
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _