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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SOCS2
All Species:
25.76
Human Site:
Y157
Identified Species:
56.67
UniProt:
O14508
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14508
NP_003868.1
198
22172
Y157
L
Y
L
T
K
P
L
Y
T
S
A
P
S
L
Q
Chimpanzee
Pan troglodytes
XP_001139731
243
27147
Y157
L
Y
L
T
K
P
L
Y
T
S
A
P
S
L
Q
Rhesus Macaque
Macaca mulatta
XP_001097728
264
29346
A197
L
P
M
P
K
E
D
A
P
N
D
P
A
L
P
Dog
Lupus familis
XP_539720
198
22236
Y157
L
Y
L
T
K
P
L
Y
T
S
A
P
P
L
Q
Cat
Felis silvestris
Mouse
Mus musculus
O35717
198
22415
Y157
L
Y
L
T
K
P
L
Y
T
S
A
P
T
L
Q
Rat
Rattus norvegicus
O88582
198
22361
Y157
L
Y
L
T
K
P
L
Y
T
S
A
P
T
L
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511644
191
21779
T151
Y
L
T
K
P
L
Y
T
S
T
P
S
L
Q
H
Chicken
Gallus gallus
Q9PW70
249
28100
A193
P
P
V
Q
K
E
V
A
V
A
A
V
H
L
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001108022
197
22308
Y156
L
L
L
T
T
P
V
Y
T
A
T
P
S
L
Q
Tiger Blowfish
Takifugu rubipres
NP_001116332
201
22377
Y160
L
L
L
T
T
P
V
Y
T
A
T
P
T
L
Q
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_799032
227
25956
L164
P
K
T
R
S
G
Q
L
V
W
L
E
P
S
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80.6
39
94.4
N.A.
93.9
93.4
N.A.
79.8
41.7
N.A.
57
53.2
N.A.
N.A.
N.A.
37.4
Protein Similarity:
100
81.4
51.5
95.9
N.A.
95.4
95.9
N.A.
87.3
51.4
N.A.
71.7
69.6
N.A.
N.A.
N.A.
50.2
P-Site Identity:
100
100
26.6
93.3
N.A.
93.3
93.3
N.A.
0
20
N.A.
66.6
60
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
46.6
93.3
N.A.
100
100
N.A.
13.3
46.6
N.A.
80
80
N.A.
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
19
0
28
55
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
10
0
0
0
10
0
0
0
0
% D
% Glu:
0
0
0
0
0
19
0
0
0
0
0
10
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
10
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
10
0
10
64
0
0
0
0
0
0
0
0
0
10
% K
% Leu:
73
28
64
0
0
10
46
10
0
0
10
0
10
82
0
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% N
% Pro:
19
19
0
10
10
64
0
0
10
0
10
73
19
0
10
% P
% Gln:
0
0
0
10
0
0
10
0
0
0
0
0
0
10
64
% Q
% Arg:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
10
0
0
0
10
46
0
10
28
10
0
% S
% Thr:
0
0
19
64
19
0
0
10
64
10
19
0
28
0
0
% T
% Val:
0
0
10
0
0
0
28
0
19
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% W
% Tyr:
10
46
0
0
0
0
10
64
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _