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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SOCS2
All Species:
16.36
Human Site:
T22
Identified Species:
36
UniProt:
O14508
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14508
NP_003868.1
198
22172
T22
G
T
R
S
Q
W
G
T
A
G
S
A
E
E
P
Chimpanzee
Pan troglodytes
XP_001139731
243
27147
T22
G
T
R
S
Q
W
G
T
A
G
S
A
E
E
P
Rhesus Macaque
Macaca mulatta
XP_001097728
264
29346
S62
G
T
P
A
Q
I
E
S
E
P
K
V
L
D
P
Dog
Lupus familis
XP_539720
198
22236
P22
G
T
P
S
Q
W
G
P
A
G
P
A
E
E
P
Cat
Felis silvestris
Mouse
Mus musculus
O35717
198
22415
T22
R
T
R
S
Q
W
G
T
A
G
L
P
E
E
Q
Rat
Rattus norvegicus
O88582
198
22361
T22
R
T
R
S
Q
W
G
T
A
G
S
P
E
D
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511644
191
21779
G17
A
G
S
D
G
S
E
G
A
A
D
E
Q
P
P
Chicken
Gallus gallus
Q9PW70
249
28100
L22
E
K
I
Q
R
L
S
L
R
G
I
A
E
D
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001108022
197
22308
T22
E
R
R
S
Q
S
E
T
Q
V
A
D
T
E
Q
Tiger Blowfish
Takifugu rubipres
NP_001116332
201
22377
S22
D
R
G
A
S
D
A
S
R
A
V
E
S
D
E
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_799032
227
25956
P22
A
R
R
G
M
P
A
P
A
G
Q
V
Q
L
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80.6
39
94.4
N.A.
93.9
93.4
N.A.
79.8
41.7
N.A.
57
53.2
N.A.
N.A.
N.A.
37.4
Protein Similarity:
100
81.4
51.5
95.9
N.A.
95.4
95.9
N.A.
87.3
51.4
N.A.
71.7
69.6
N.A.
N.A.
N.A.
50.2
P-Site Identity:
100
100
26.6
80
N.A.
73.3
73.3
N.A.
13.3
20
N.A.
33.3
0
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
100
100
46.6
80
N.A.
73.3
80
N.A.
20
33.3
N.A.
40
20
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
0
0
19
0
0
19
0
64
19
10
37
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
10
0
10
0
0
0
0
10
10
0
37
0
% D
% Glu:
19
0
0
0
0
0
28
0
10
0
0
19
55
46
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
37
10
10
10
10
0
46
10
0
64
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
10
0
0
0
0
10
0
0
0
0
% I
% Lys:
0
10
0
0
0
0
0
0
0
0
10
0
0
0
0
% K
% Leu:
0
0
0
0
0
10
0
10
0
0
10
0
10
10
10
% L
% Met:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
19
0
0
10
0
19
0
10
10
19
0
10
55
% P
% Gln:
0
0
0
10
64
0
0
0
10
0
10
0
19
0
28
% Q
% Arg:
19
28
55
0
10
0
0
0
19
0
0
0
0
0
0
% R
% Ser:
0
0
10
55
10
19
10
19
0
0
28
0
10
0
0
% S
% Thr:
0
55
0
0
0
0
0
46
0
0
0
0
10
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
10
10
19
0
0
0
% V
% Trp:
0
0
0
0
0
46
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _