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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPAP2A
All Species:
17.27
Human Site:
Y121
Identified Species:
29.23
UniProt:
O14494
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14494
NP_003702.2
284
32156
Y121
S
L
T
D
I
A
K
Y
S
I
G
R
L
R
P
Chimpanzee
Pan troglodytes
XP_517759
284
32152
Y121
S
L
T
D
I
A
K
Y
S
I
G
R
L
R
P
Rhesus Macaque
Macaca mulatta
XP_001116998
289
31981
M119
L
T
D
L
A
K
Y
M
I
G
R
L
R
P
N
Dog
Lupus familis
XP_849687
215
24386
L56
A
K
Y
S
I
G
R
L
R
P
H
F
L
D
V
Cat
Felis silvestris
Mouse
Mus musculus
Q61469
283
31873
Y121
S
L
T
D
I
A
K
Y
T
I
G
S
L
R
P
Rat
Rattus norvegicus
O08564
282
31978
Y121
S
L
T
D
I
A
K
Y
S
I
G
R
L
R
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513815
435
48425
G180
E
P
S
L
R
T
P
G
T
H
Q
V
S
V
A
Chicken
Gallus gallus
XP_424730
246
27534
N87
F
Y
N
H
L
H
S
N
S
F
V
R
N
N
Y
Frog
Xenopus laevis
Q6GM05
314
34960
V140
I
F
V
N
A
G
Q
V
V
T
G
N
L
A
P
Zebra Danio
Brachydanio rerio
Q6IQH6
333
36474
V146
I
F
V
N
A
G
Q
V
V
T
G
N
L
A
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V576
379
42771
Y212
L
T
T
D
I
A
K
Y
S
I
G
R
L
R
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10022
341
39009
A138
I
G
F
V
M
N
I
A
L
N
I
V
T
K
H
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9XI60
290
32684
D119
V
I
T
D
A
I
K
D
A
V
G
R
P
R
P
Baker's Yeast
Sacchar. cerevisiae
Q05521
289
33495
N119
F
F
T
N
F
I
K
N
W
I
G
R
L
R
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
53.2
68.6
N.A.
82.7
83
N.A.
20
72.1
27
27.3
N.A.
34.8
N.A.
28.4
N.A.
Protein Similarity:
100
100
68.5
72.8
N.A.
91.5
90.4
N.A.
33.3
80.2
48.7
46.2
N.A.
48.5
N.A.
46.6
N.A.
P-Site Identity:
100
100
0
13.3
N.A.
86.6
100
N.A.
0
13.3
20
20
N.A.
86.6
N.A.
0
N.A.
P-Site Similarity:
100
100
0
26.6
N.A.
93.3
100
N.A.
13.3
20
33.3
33.3
N.A.
86.6
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.1
25.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
41.3
46.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
46.6
53.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
29
36
0
8
8
0
0
0
0
15
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
43
0
0
0
8
0
0
0
0
0
8
0
% D
% Glu:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
15
22
8
0
8
0
0
0
0
8
0
8
0
0
0
% F
% Gly:
0
8
0
0
0
22
0
8
0
8
65
0
0
0
0
% G
% His:
0
0
0
8
0
8
0
0
0
8
8
0
0
0
8
% H
% Ile:
22
8
0
0
43
15
8
0
8
43
8
0
0
0
0
% I
% Lys:
0
8
0
0
0
8
50
0
0
0
0
0
0
8
0
% K
% Leu:
15
29
0
15
8
0
0
8
8
0
0
8
65
0
0
% L
% Met:
0
0
0
0
8
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
22
0
8
0
15
0
8
0
15
8
8
8
% N
% Pro:
0
8
0
0
0
0
8
0
0
8
0
0
8
8
65
% P
% Gln:
0
0
0
0
0
0
15
0
0
0
8
0
0
0
0
% Q
% Arg:
0
0
0
0
8
0
8
0
8
0
8
50
8
50
0
% R
% Ser:
29
0
8
8
0
0
8
0
36
0
0
8
8
0
0
% S
% Thr:
0
15
50
0
0
8
0
0
15
15
0
0
8
0
0
% T
% Val:
8
0
15
8
0
0
0
15
15
8
8
15
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
0
8
8
0
0
0
8
36
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _