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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPAP2A
All Species:
10.91
Human Site:
T273
Identified Species:
18.46
UniProt:
O14494
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14494
NP_003702.2
284
32156
T273
T
T
L
H
E
T
P
T
T
G
N
H
Y
P
S
Chimpanzee
Pan troglodytes
XP_517759
284
32152
T273
T
T
L
H
E
T
P
T
T
G
N
H
Y
P
S
Rhesus Macaque
Macaca mulatta
XP_001116998
289
31981
T272
R
K
P
S
L
S
L
T
L
T
L
G
E
A
D
Dog
Lupus familis
XP_849687
215
24386
T205
T
L
H
E
T
P
T
T
G
N
H
F
R
N
N
Cat
Felis silvestris
Mouse
Mus musculus
Q61469
283
31873
S273
T
T
L
H
E
T
A
S
S
R
N
Y
S
T
N
Rat
Rattus norvegicus
O08564
282
31978
N272
T
T
L
H
E
T
T
N
R
Q
S
Y
A
R
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513815
435
48425
S401
L
L
R
G
R
A
L
S
Q
S
G
D
F
H
V
Chicken
Gallus gallus
XP_424730
246
27534
A236
L
T
G
L
I
Q
G
A
L
V
A
I
L
I
V
Frog
Xenopus laevis
Q6GM05
314
34960
I295
A
Q
M
P
I
I
S
I
P
R
V
E
N
P
L
Zebra Danio
Brachydanio rerio
Q6IQH6
333
36474
F301
R
G
L
P
L
M
T
F
P
R
V
E
S
P
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V576
379
42771
S369
T
V
Q
D
M
N
A
S
P
A
Q
A
I
T
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10022
341
39009
N300
R
P
P
R
T
P
R
N
S
E
D
E
E
R
H
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9XI60
290
32684
Q271
A
D
S
R
N
D
V
Q
D
S
A
G
M
N
H
Baker's Yeast
Sacchar. cerevisiae
Q05521
289
33495
H273
T
L
E
E
A
V
T
H
Q
R
I
P
D
E
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
53.2
68.6
N.A.
82.7
83
N.A.
20
72.1
27
27.3
N.A.
34.8
N.A.
28.4
N.A.
Protein Similarity:
100
100
68.5
72.8
N.A.
91.5
90.4
N.A.
33.3
80.2
48.7
46.2
N.A.
48.5
N.A.
46.6
N.A.
P-Site Identity:
100
100
6.6
13.3
N.A.
46.6
40
N.A.
0
6.6
6.6
13.3
N.A.
6.6
N.A.
0
N.A.
P-Site Similarity:
100
100
13.3
26.6
N.A.
73.3
60
N.A.
13.3
6.6
13.3
13.3
N.A.
13.3
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.1
25.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
41.3
46.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
0
0
0
8
8
15
8
0
8
15
8
8
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
8
0
8
0
0
8
0
8
8
8
0
8
% D
% Glu:
0
0
8
15
29
0
0
0
0
8
0
22
15
8
8
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
8
8
0
0
% F
% Gly:
0
8
8
8
0
0
8
0
8
15
8
15
0
0
0
% G
% His:
0
0
8
29
0
0
0
8
0
0
8
15
0
8
15
% H
% Ile:
0
0
0
0
15
8
0
8
0
0
8
8
8
8
8
% I
% Lys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
15
22
36
8
15
0
15
0
15
0
8
0
8
0
15
% L
% Met:
0
0
8
0
8
8
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
8
8
0
15
0
8
22
0
8
15
22
% N
% Pro:
0
8
15
15
0
15
15
0
22
0
0
8
0
29
0
% P
% Gln:
0
8
8
0
0
8
0
8
15
8
8
0
0
0
0
% Q
% Arg:
22
0
8
15
8
0
8
0
8
29
0
0
8
15
0
% R
% Ser:
0
0
8
8
0
8
8
22
15
15
8
0
15
0
15
% S
% Thr:
50
36
0
0
15
29
29
29
15
8
0
0
0
15
0
% T
% Val:
0
8
0
0
0
8
8
0
0
8
15
0
0
0
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
15
15
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _