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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ACACB All Species: 13.33
Human Site: Y317 Identified Species: 29.33
UniProt: O00763 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.3
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00763 NP_001084.3 2458 276555 Y317 Y I K M A D H Y V P V P G G P
Chimpanzee Pan troglodytes XP_511428 2532 285118 Y361 Y I K M A D H Y V P V P G G P
Rhesus Macaque Macaca mulatta XP_001111672 2327 263361 Q299 K D V D D G L Q A A E E V G Y
Dog Lupus familis XP_867594 2323 262742 K299 K D V D D G L K A A E E V G Y
Cat Felis silvestris
Mouse Mus musculus Q5SWU9 2345 265238 A300 V D D G L K A A E E V G Y P V
Rat Rattus norvegicus P11497 2345 265175 A300 V D D G L K A A E E V G Y P V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508230 2450 275669 Y309 Y I K M A D H Y V P V P G G P
Chicken Gallus gallus P11029 2324 262701 R299 K D A D D G L R A A E E V G Y
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_684081 2240 253300 G298 G N A I S L F G R D C S I Q R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001097227 2571 287535 Y406 Y I K M A D H Y V P V P G G S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q00955 2233 250335 K291 G S P I F I M K L A G R A R H
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 70.5 72.3 72.2 N.A. 72.1 72.1 N.A. 83.8 71.8 N.A. 71.7 N.A. 56.3 N.A. N.A. N.A.
Protein Similarity: 100 81.9 82.9 82.7 N.A. 82.8 82.8 N.A. 91.7 83 N.A. 81.5 N.A. 71.8 N.A. N.A. N.A.
P-Site Identity: 100 100 6.6 6.6 N.A. 6.6 6.6 N.A. 100 6.6 N.A. 0 N.A. 93.3 N.A. N.A. N.A.
P-Site Similarity: 100 100 6.6 6.6 N.A. 6.6 6.6 N.A. 100 6.6 N.A. 13.3 N.A. 93.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 43.7 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 59.8 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 19 0 37 0 19 19 28 37 0 0 10 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % C
% Asp: 0 46 19 28 28 37 0 0 0 10 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 19 19 28 28 0 0 0 % E
% Phe: 0 0 0 0 10 0 10 0 0 0 0 0 0 0 0 % F
% Gly: 19 0 0 19 0 28 0 10 0 0 10 19 37 64 0 % G
% His: 0 0 0 0 0 0 37 0 0 0 0 0 0 0 10 % H
% Ile: 0 37 0 19 0 10 0 0 0 0 0 0 10 0 0 % I
% Lys: 28 0 37 0 0 19 0 19 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 19 10 28 0 10 0 0 0 0 0 0 % L
% Met: 0 0 0 37 0 0 10 0 0 0 0 0 0 0 0 % M
% Asn: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 10 0 0 0 0 0 0 37 0 37 0 19 28 % P
% Gln: 0 0 0 0 0 0 0 10 0 0 0 0 0 10 0 % Q
% Arg: 0 0 0 0 0 0 0 10 10 0 0 10 0 10 10 % R
% Ser: 0 10 0 0 10 0 0 0 0 0 0 10 0 0 10 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 19 0 19 0 0 0 0 0 37 0 55 0 28 0 19 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 37 0 0 0 0 0 0 37 0 0 0 0 19 0 28 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _