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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ACACB All Species: 33.94
Human Site: T1865 Identified Species: 74.67
UniProt: O00763 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00763 NP_001084.3 2458 276555 T1865 G F K Y L Y L T P Q D Y T R I
Chimpanzee Pan troglodytes XP_511428 2532 285118 T1940 G Y R Y L Y L T P Q D Y K R V
Rhesus Macaque Macaca mulatta XP_001111672 2327 263361 T1735 G Y R Y L Y L T P Q D Y K R V
Dog Lupus familis XP_867594 2323 262742 T1731 G Y K Y L Y L T P Q D Y K R V
Cat Felis silvestris
Mouse Mus musculus Q5SWU9 2345 265238 T1753 G Y K Y L Y L T P Q D Y K R V
Rat Rattus norvegicus P11497 2345 265175 T1753 G Y K Y L Y L T P Q D Y K R V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508230 2450 275669 T1857 G F K Y L Y L T P Q D Y T R I
Chicken Gallus gallus P11029 2324 262701 T1731 G Y K Y L Y L T P Q D Y K K V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_684081 2240 253300 G1686 I G K E E G I G V E N L R G S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001097227 2571 287535 S1974 G F K Y L Y L S T E D Y A Q V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q00955 2233 250335 R1679 E N S V L T E R T V I N G E E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 70.5 72.3 72.2 N.A. 72.1 72.1 N.A. 83.8 71.8 N.A. 71.7 N.A. 56.3 N.A. N.A. N.A.
Protein Similarity: 100 81.9 82.9 82.7 N.A. 82.8 82.8 N.A. 91.7 83 N.A. 81.5 N.A. 71.8 N.A. N.A. N.A.
P-Site Identity: 100 73.3 73.3 80 N.A. 80 80 N.A. 100 73.3 N.A. 6.6 N.A. 60 N.A. N.A. N.A.
P-Site Similarity: 100 93.3 93.3 93.3 N.A. 93.3 93.3 N.A. 100 93.3 N.A. 26.6 N.A. 86.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 43.7 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 59.8 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 82 0 0 0 0 % D
% Glu: 10 0 0 10 10 0 10 0 0 19 0 0 0 10 10 % E
% Phe: 0 28 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 82 10 0 0 0 10 0 10 0 0 0 0 10 10 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 0 0 0 0 0 10 0 0 0 10 0 0 0 19 % I
% Lys: 0 0 73 0 0 0 0 0 0 0 0 0 55 10 0 % K
% Leu: 0 0 0 0 91 0 82 0 0 0 0 10 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 10 0 0 0 0 0 0 0 0 10 10 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 73 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 73 0 0 0 10 0 % Q
% Arg: 0 0 19 0 0 0 0 10 0 0 0 0 10 64 0 % R
% Ser: 0 0 10 0 0 0 0 10 0 0 0 0 0 0 10 % S
% Thr: 0 0 0 0 0 10 0 73 19 0 0 0 19 0 0 % T
% Val: 0 0 0 10 0 0 0 0 10 10 0 0 0 0 64 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 55 0 82 0 82 0 0 0 0 0 82 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _