KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NME4
All Species:
19.39
Human Site:
S120
Identified Species:
35.56
UniProt:
O00746
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00746
NP_005000.1
187
20659
S120
G
Y
N
V
V
R
A
S
R
A
M
I
G
H
T
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001085126
187
20710
S120
G
Y
N
V
V
R
A
S
R
A
M
I
G
H
T
Dog
Lupus familis
XP_534114
773
84104
S706
G
P
S
V
V
C
S
S
R
T
M
I
G
H
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9WV84
186
20530
S119
G
P
N
V
V
H
I
S
R
A
M
I
G
H
T
Rat
Rattus norvegicus
Q05982
152
17174
T86
E
G
L
N
V
V
K
T
G
R
V
M
L
G
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515701
267
30034
F175
I
D
L
K
D
R
P
F
F
P
G
L
V
K
Y
Chicken
Gallus gallus
O57535
153
17269
T87
E
G
L
N
V
V
K
T
G
R
V
M
L
G
E
Frog
Xenopus laevis
P70010
154
17471
G88
G
L
N
V
V
K
T
G
R
V
M
L
G
E
T
Zebra Danio
Brachydanio rerio
XP_002661154
193
21501
S127
G
H
N
V
V
K
T
S
R
M
M
V
G
D
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P08879
153
17151
T87
E
G
L
N
V
V
K
T
G
R
Q
M
L
G
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O64903
231
25532
L117
K
G
F
K
L
I
G
L
K
M
F
Q
C
P
K
Baker's Yeast
Sacchar. cerevisiae
P36010
153
17148
Q87
E
G
K
D
V
V
R
Q
G
R
T
I
L
G
A
Red Bread Mold
Neurospora crassa
Q9UUY8
152
16882
T86
E
G
K
D
A
V
K
T
G
R
T
I
L
G
A
Conservation
Percent
Protein Identity:
100
N.A.
97.3
20.9
N.A.
82.3
47.5
N.A.
39.7
46.5
45.9
61.1
N.A.
44.3
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
97.8
22.2
N.A.
87.6
63
N.A.
52
62.5
61.5
74.6
N.A.
59.8
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
100
66.6
N.A.
80
6.6
N.A.
6.6
6.6
53.3
60
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
100
80
N.A.
80
26.6
N.A.
13.3
26.6
66.6
80
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
40.2
41.7
43.3
Protein Similarity:
N.A.
N.A.
N.A.
51.9
58.8
57.7
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
13.3
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
16
0
0
24
0
0
0
0
24
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
8
0
16
8
0
0
0
0
0
0
0
0
8
0
% D
% Glu:
39
0
0
0
0
0
0
0
0
0
0
0
0
8
16
% E
% Phe:
0
0
8
0
0
0
0
8
8
0
8
0
0
0
0
% F
% Gly:
47
47
0
0
0
0
8
8
39
0
8
0
47
39
0
% G
% His:
0
8
0
0
0
8
0
0
0
0
0
0
0
31
0
% H
% Ile:
8
0
0
0
0
8
8
0
0
0
0
47
0
0
0
% I
% Lys:
8
0
16
16
0
16
31
0
8
0
0
0
0
8
8
% K
% Leu:
0
8
31
0
8
0
0
8
0
0
0
16
39
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
16
47
24
0
0
0
% M
% Asn:
0
0
39
24
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
16
0
0
0
0
8
0
0
8
0
0
0
8
0
% P
% Gln:
0
0
0
0
0
0
0
8
0
0
8
8
0
0
0
% Q
% Arg:
0
0
0
0
0
24
8
0
47
39
0
0
0
0
0
% R
% Ser:
0
0
8
0
0
0
8
39
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
16
31
0
8
16
0
0
0
47
% T
% Val:
0
0
0
47
77
39
0
0
0
8
16
8
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
16
0
0
0
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _