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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PEX12
All Species:
19.09
Human Site:
Y74
Identified Species:
28
UniProt:
O00623
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00623
NP_000277.1
359
40797
Y74
D
L
L
L
Q
Q
H
Y
L
S
R
T
S
A
S
Chimpanzee
Pan troglodytes
XP_001174172
359
40821
Y74
D
L
L
L
Q
Q
H
Y
L
S
R
T
S
A
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_548259
359
40831
Y74
D
L
L
L
Q
Q
H
Y
L
S
K
T
S
A
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8VC48
359
40614
Y74
D
F
L
L
Q
Q
H
Y
L
S
R
T
S
A
S
Rat
Rattus norvegicus
O88177
359
40663
Y74
D
F
L
L
Q
Q
H
Y
L
S
R
T
S
A
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511496
312
33803
M31
V
V
A
Q
D
S
L
M
T
A
V
R
P
A
L
Chicken
Gallus gallus
XP_415773
356
39947
H73
L
D
F
L
L
Q
Q
H
Y
L
A
R
C
S
A
Frog
Xenopus laevis
NP_001086511
353
40718
Q72
L
L
E
C
L
L
Q
Q
H
Y
L
S
W
A
S
Zebra Danio
Brachydanio rerio
NP_956499
303
34092
F21
A
E
D
R
P
S
V
F
E
V
L
A
Q
D
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VPT5
297
34525
S16
Q
N
L
Q
N
V
P
S
I
F
E
I
S
A
S
Honey Bee
Apis mellifera
XP_624974
285
32991
Nematode Worm
Caenorhab. elegans
Q19189
359
41271
L75
Y
I
I
F
D
L
I
L
Q
N
H
Y
L
R
N
Sea Urchin
Strong. purpuratus
XP_788130
354
40571
H72
L
D
L
I
L
Q
H
H
F
L
T
K
T
S
A
Poplar Tree
Populus trichocarpa
XP_002325774
388
43941
F75
L
R
T
T
D
A
S
F
S
E
S
L
Y
G
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M841
393
44382
F75
L
R
T
T
D
G
S
F
A
E
S
L
Y
G
L
Baker's Yeast
Sacchar. cerevisiae
Q04370
399
45974
H90
K
G
F
V
E
W
Y
H
L
K
T
Y
N
S
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
N.A.
92.1
N.A.
89.4
88.5
N.A.
46.7
76
64
51.5
N.A.
29.8
31.7
35.9
45.6
Protein Similarity:
100
99.7
N.A.
96
N.A.
93.3
92.7
N.A.
57.3
85.7
79.6
65.4
N.A.
47
49
56.2
68.5
P-Site Identity:
100
100
N.A.
93.3
N.A.
93.3
93.3
N.A.
6.6
13.3
20
6.6
N.A.
26.6
0
0
20
P-Site Similarity:
100
100
N.A.
100
N.A.
93.3
93.3
N.A.
20
33.3
26.6
13.3
N.A.
33.3
0
26.6
53.3
Percent
Protein Identity:
31.9
N.A.
N.A.
31.3
22.3
N.A.
Protein Similarity:
48.7
N.A.
N.A.
48.3
40.3
N.A.
P-Site Identity:
0
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
6.6
N.A.
N.A.
6.6
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
7
0
0
7
0
0
7
7
7
7
0
50
13
% A
% Cys:
0
0
0
7
0
0
0
0
0
0
0
0
7
0
0
% C
% Asp:
32
13
7
0
25
0
0
0
0
0
0
0
0
7
0
% D
% Glu:
0
7
7
0
7
0
0
0
7
13
7
0
0
0
0
% E
% Phe:
0
13
13
7
0
0
0
19
7
7
0
0
0
0
0
% F
% Gly:
0
7
0
0
0
7
0
0
0
0
0
0
0
13
0
% G
% His:
0
0
0
0
0
0
38
19
7
0
7
0
0
0
0
% H
% Ile:
0
7
7
7
0
0
7
0
7
0
0
7
0
0
0
% I
% Lys:
7
0
0
0
0
0
0
0
0
7
7
7
0
0
0
% K
% Leu:
32
25
44
38
19
13
7
7
38
13
13
13
7
0
19
% L
% Met:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% M
% Asn:
0
7
0
0
7
0
0
0
0
7
0
0
7
0
7
% N
% Pro:
0
0
0
0
7
0
7
0
0
0
0
0
7
0
0
% P
% Gln:
7
0
0
13
32
44
13
7
7
0
0
0
7
0
0
% Q
% Arg:
0
13
0
7
0
0
0
0
0
0
25
13
0
7
0
% R
% Ser:
0
0
0
0
0
13
13
7
7
32
13
7
38
19
50
% S
% Thr:
0
0
13
13
0
0
0
0
7
0
13
32
7
0
7
% T
% Val:
7
7
0
7
0
7
7
0
0
7
7
0
0
0
0
% V
% Trp:
0
0
0
0
0
7
0
0
0
0
0
0
7
0
0
% W
% Tyr:
7
0
0
0
0
0
7
32
7
7
0
13
13
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _