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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PEX12
All Species:
23.94
Human Site:
Y156
Identified Species:
35.11
UniProt:
O00623
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00623
NP_000277.1
359
40797
Y156
S
S
R
W
K
R
F
Y
R
A
F
L
A
A
Y
Chimpanzee
Pan troglodytes
XP_001174172
359
40821
Y156
S
S
R
W
K
R
F
Y
R
A
F
L
A
A
Y
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_548259
359
40831
Y156
S
S
R
W
K
Q
F
Y
R
A
F
L
A
A
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q8VC48
359
40614
Y156
S
S
R
W
K
R
F
Y
R
A
F
L
A
A
Y
Rat
Rattus norvegicus
O88177
359
40663
Y156
S
S
H
W
K
R
F
Y
R
V
F
L
A
A
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511496
312
33803
L113
P
G
L
P
R
E
Q
L
R
R
S
L
L
L
L
Chicken
Gallus gallus
XP_415773
356
39947
Y155
S
S
S
W
K
R
F
Y
R
A
F
L
A
A
Y
Frog
Xenopus laevis
NP_001086511
353
40718
I154
H
K
R
C
Y
K
A
I
L
A
S
Y
P
F
L
Zebra Danio
Brachydanio rerio
NP_956499
303
34092
G103
S
A
R
A
A
H
L
G
L
R
R
R
Q
H
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VPT5
297
34525
N98
T
T
T
G
D
L
L
N
R
R
Q
Q
F
A
S
Honey Bee
Apis mellifera
XP_624974
285
32991
K86
K
V
K
L
E
K
Y
K
L
E
E
V
D
D
C
Nematode Worm
Caenorhab. elegans
Q19189
359
41271
M157
M
K
A
K
C
Q
K
M
F
V
I
I
W
P
Y
Sea Urchin
Strong. purpuratus
XP_788130
354
40571
Y154
G
R
Q
T
M
K
K
Y
K
K
I
F
L
A
L
Poplar Tree
Populus trichocarpa
XP_002325774
388
43941
D157
N
G
D
E
T
V
E
D
A
E
Y
F
S
G
G
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M841
393
44382
E157
A
E
D
Q
G
F
D
E
A
D
F
F
T
G
D
Baker's Yeast
Sacchar. cerevisiae
Q04370
399
45974
S172
S
M
N
N
I
F
S
S
D
E
T
E
N
K
W
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
N.A.
92.1
N.A.
89.4
88.5
N.A.
46.7
76
64
51.5
N.A.
29.8
31.7
35.9
45.6
Protein Similarity:
100
99.7
N.A.
96
N.A.
93.3
92.7
N.A.
57.3
85.7
79.6
65.4
N.A.
47
49
56.2
68.5
P-Site Identity:
100
100
N.A.
93.3
N.A.
100
86.6
N.A.
13.3
93.3
13.3
13.3
N.A.
13.3
0
6.6
13.3
P-Site Similarity:
100
100
N.A.
100
N.A.
100
86.6
N.A.
20
93.3
20
26.6
N.A.
26.6
33.3
20
33.3
Percent
Protein Identity:
31.9
N.A.
N.A.
31.3
22.3
N.A.
Protein Similarity:
48.7
N.A.
N.A.
48.3
40.3
N.A.
P-Site Identity:
0
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
20
N.A.
N.A.
13.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
7
7
7
0
7
0
13
38
0
0
38
50
0
% A
% Cys:
0
0
0
7
7
0
0
0
0
0
0
0
0
0
7
% C
% Asp:
0
0
13
0
7
0
7
7
7
7
0
0
7
7
7
% D
% Glu:
0
7
0
7
7
7
7
7
0
19
7
7
0
0
0
% E
% Phe:
0
0
0
0
0
13
38
0
7
0
44
19
7
7
0
% F
% Gly:
7
13
0
7
7
0
0
7
0
0
0
0
0
13
7
% G
% His:
7
0
7
0
0
7
0
0
0
0
0
0
0
7
0
% H
% Ile:
0
0
0
0
7
0
0
7
0
0
13
7
0
0
0
% I
% Lys:
7
13
7
7
38
19
13
7
7
7
0
0
0
7
0
% K
% Leu:
0
0
7
7
0
7
13
7
19
0
0
44
13
7
19
% L
% Met:
7
7
0
0
7
0
0
7
0
0
0
0
0
0
0
% M
% Asn:
7
0
7
7
0
0
0
7
0
0
0
0
7
0
0
% N
% Pro:
7
0
0
7
0
0
0
0
0
0
0
0
7
7
0
% P
% Gln:
0
0
7
7
0
13
7
0
0
0
7
7
7
0
0
% Q
% Arg:
0
7
38
0
7
32
0
0
50
19
7
7
0
0
0
% R
% Ser:
50
38
7
0
0
0
7
7
0
0
13
0
7
0
7
% S
% Thr:
7
7
7
7
7
0
0
0
0
0
7
0
7
0
0
% T
% Val:
0
7
0
0
0
7
0
0
0
13
0
7
0
0
0
% V
% Trp:
0
0
0
38
0
0
0
0
0
0
0
0
7
0
13
% W
% Tyr:
0
0
0
0
7
0
7
44
0
0
7
7
0
0
44
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _