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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PEX12
All Species:
22.73
Human Site:
Y143
Identified Species:
33.33
UniProt:
O00623
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00623
NP_000277.1
359
40797
Y143
S
L
R
E
E
D
E
Y
S
I
H
P
P
S
S
Chimpanzee
Pan troglodytes
XP_001174172
359
40821
Y143
S
L
R
E
E
D
E
Y
S
I
H
P
P
S
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_548259
359
40831
Y143
S
L
R
E
E
D
E
Y
S
I
H
P
P
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8VC48
359
40614
Y143
S
L
R
E
E
D
E
Y
S
I
H
P
P
S
S
Rat
Rattus norvegicus
O88177
359
40663
Y143
T
L
R
E
E
D
E
Y
S
I
H
P
P
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511496
312
33803
G100
V
A
T
G
A
G
P
G
R
P
A
G
G
P
G
Chicken
Gallus gallus
XP_415773
356
39947
Y142
S
L
R
E
E
D
E
Y
S
I
H
P
P
S
S
Frog
Xenopus laevis
NP_001086511
353
40718
Q141
E
E
E
D
Y
S
I
Q
N
P
T
S
F
H
K
Zebra Danio
Brachydanio rerio
NP_956499
303
34092
K90
S
E
N
F
Y
G
L
K
R
V
G
S
H
S
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VPT5
297
34525
G85
S
F
G
E
S
F
Y
G
L
Q
R
T
V
T
T
Honey Bee
Apis mellifera
XP_624974
285
32991
I73
T
F
Y
S
L
K
R
I
I
I
V
N
S
K
V
Nematode Worm
Caenorhab. elegans
Q19189
359
41271
W144
E
V
Y
E
C
R
S
W
S
S
I
N
G
M
K
Sea Urchin
Strong. purpuratus
XP_788130
354
40571
L141
Q
K
W
T
D
E
S
L
D
L
N
D
R
G
R
Poplar Tree
Populus trichocarpa
XP_002325774
388
43941
Q144
K
E
R
E
A
R
L
Q
A
S
L
W
G
N
G
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M841
393
44382
R144
K
E
R
E
A
R
L
R
E
S
L
W
G
A
E
Baker's Yeast
Sacchar. cerevisiae
Q04370
399
45974
E159
Y
I
T
A
K
L
D
E
I
L
E
K
I
S
M
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
N.A.
92.1
N.A.
89.4
88.5
N.A.
46.7
76
64
51.5
N.A.
29.8
31.7
35.9
45.6
Protein Similarity:
100
99.7
N.A.
96
N.A.
93.3
92.7
N.A.
57.3
85.7
79.6
65.4
N.A.
47
49
56.2
68.5
P-Site Identity:
100
100
N.A.
100
N.A.
100
93.3
N.A.
0
100
0
13.3
N.A.
13.3
6.6
13.3
0
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
0
100
13.3
26.6
N.A.
26.6
13.3
26.6
26.6
Percent
Protein Identity:
31.9
N.A.
N.A.
31.3
22.3
N.A.
Protein Similarity:
48.7
N.A.
N.A.
48.3
40.3
N.A.
P-Site Identity:
13.3
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
20
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
7
19
0
0
0
7
0
7
0
0
7
7
% A
% Cys:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
7
7
38
7
0
7
0
0
7
0
0
0
% D
% Glu:
13
25
7
63
38
7
38
7
7
0
7
0
0
0
7
% E
% Phe:
0
13
0
7
0
7
0
0
0
0
0
0
7
0
0
% F
% Gly:
0
0
7
7
0
13
0
13
0
0
7
7
25
7
13
% G
% His:
0
0
0
0
0
0
0
0
0
0
38
0
7
7
0
% H
% Ile:
0
7
0
0
0
0
7
7
13
44
7
0
7
0
0
% I
% Lys:
13
7
0
0
7
7
0
7
0
0
0
7
0
7
13
% K
% Leu:
0
38
0
0
7
7
19
7
7
13
13
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
7
% M
% Asn:
0
0
7
0
0
0
0
0
7
0
7
13
0
7
0
% N
% Pro:
0
0
0
0
0
0
7
0
0
13
0
38
38
7
0
% P
% Gln:
7
0
0
0
0
0
0
13
0
7
0
0
0
0
0
% Q
% Arg:
0
0
50
0
0
19
7
7
13
0
7
0
7
0
7
% R
% Ser:
44
0
0
7
7
7
13
0
44
19
0
13
7
50
38
% S
% Thr:
13
0
13
7
0
0
0
0
0
0
7
7
0
7
7
% T
% Val:
7
7
0
0
0
0
0
0
0
7
7
0
7
0
7
% V
% Trp:
0
0
7
0
0
0
0
7
0
0
0
13
0
0
0
% W
% Tyr:
7
0
13
0
13
0
7
38
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _