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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PEX12
All Species:
30.61
Human Site:
T277
Identified Species:
44.89
UniProt:
O00623
Number Species:
15
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00623
NP_000277.1
359
40797
T277
Q
E
T
I
K
S
L
T
A
L
P
T
P
P
P
Chimpanzee
Pan troglodytes
XP_001174172
359
40821
T277
Q
E
T
I
K
S
L
T
A
L
P
T
P
P
P
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_548259
359
40831
T277
Q
E
T
I
K
S
L
T
A
L
P
T
P
P
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8VC48
359
40614
T277
Q
E
A
I
K
S
L
T
A
L
P
T
P
P
P
Rat
Rattus norvegicus
O88177
359
40663
T277
Q
E
T
I
K
S
L
T
A
L
P
T
P
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511496
312
33803
E231
T
V
L
G
T
G
G
E
T
M
S
R
Y
W
L
Chicken
Gallus gallus
XP_415773
356
39947
T274
Q
E
T
I
K
S
L
T
A
L
P
T
P
P
P
Frog
Xenopus laevis
NP_001086511
353
40718
N272
E
T
L
K
S
L
G
N
L
P
V
P
P
P
P
Zebra Danio
Brachydanio rerio
NP_956499
303
34092
F222
E
L
S
S
G
Q
S
F
G
E
K
L
Q
R
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VPT5
297
34525
G216
N
D
Q
R
R
K
V
G
G
T
L
I
N
P
E
Honey Bee
Apis mellifera
XP_624974
285
32991
E204
F
L
S
W
W
T
Q
E
H
Y
S
T
N
L
L
Nematode Worm
Caenorhab. elegans
Q19189
359
41271
L276
Y
N
T
D
L
A
K
L
T
K
T
G
L
D
G
Sea Urchin
Strong. purpuratus
XP_788130
354
40571
T272
H
Q
S
A
L
A
A
T
S
L
P
I
P
E
P
Poplar Tree
Populus trichocarpa
XP_002325774
388
43941
T307
E
E
R
M
S
A
P
T
V
Y
P
P
P
P
P
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M841
393
44382
T312
E
E
R
L
S
A
P
T
V
Y
P
P
P
P
P
Baker's Yeast
Sacchar. cerevisiae
Q04370
399
45974
D307
K
L
Q
K
R
V
N
D
L
D
E
D
I
P
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
N.A.
92.1
N.A.
89.4
88.5
N.A.
46.7
76
64
51.5
N.A.
29.8
31.7
35.9
45.6
Protein Similarity:
100
99.7
N.A.
96
N.A.
93.3
92.7
N.A.
57.3
85.7
79.6
65.4
N.A.
47
49
56.2
68.5
P-Site Identity:
100
100
N.A.
100
N.A.
93.3
100
N.A.
0
100
20
0
N.A.
6.6
6.6
6.6
33.3
P-Site Similarity:
100
100
N.A.
100
N.A.
93.3
100
N.A.
6.6
100
26.6
13.3
N.A.
26.6
20
13.3
60
Percent
Protein Identity:
31.9
N.A.
N.A.
31.3
22.3
N.A.
Protein Similarity:
48.7
N.A.
N.A.
48.3
40.3
N.A.
P-Site Identity:
40
N.A.
N.A.
40
6.6
N.A.
P-Site Similarity:
60
N.A.
N.A.
60
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
7
0
25
7
0
38
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
0
7
0
0
0
7
0
7
0
7
0
7
0
% D
% Glu:
25
50
0
0
0
0
0
13
0
7
7
0
0
7
7
% E
% Phe:
7
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
7
7
7
13
7
13
0
0
7
0
0
7
% G
% His:
7
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% H
% Ile:
0
0
0
38
0
0
0
0
0
0
0
13
7
0
0
% I
% Lys:
7
0
0
13
38
7
7
0
0
7
7
0
0
0
0
% K
% Leu:
0
19
13
7
13
7
38
7
13
44
7
7
7
7
13
% L
% Met:
0
0
0
7
0
0
0
0
0
7
0
0
0
0
0
% M
% Asn:
7
7
0
0
0
0
7
7
0
0
0
0
13
0
0
% N
% Pro:
0
0
0
0
0
0
13
0
0
7
57
19
63
69
63
% P
% Gln:
38
7
13
0
0
7
7
0
0
0
0
0
7
0
0
% Q
% Arg:
0
0
13
7
13
0
0
0
0
0
0
7
0
7
7
% R
% Ser:
0
0
19
7
19
38
7
0
7
0
13
0
0
0
0
% S
% Thr:
7
7
38
0
7
7
0
57
13
7
7
44
0
0
0
% T
% Val:
0
7
0
0
0
7
7
0
13
0
7
0
0
0
7
% V
% Trp:
0
0
0
7
7
0
0
0
0
0
0
0
0
7
0
% W
% Tyr:
7
0
0
0
0
0
0
0
0
19
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _