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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PEX12
All Species:
23.03
Human Site:
S294
Identified Species:
33.78
UniProt:
O00623
Number Species:
15
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00623
NP_000277.1
359
40797
S294
H
L
D
Y
N
S
D
S
P
L
L
P
K
M
K
Chimpanzee
Pan troglodytes
XP_001174172
359
40821
S294
H
L
D
Y
N
S
D
S
P
L
L
P
K
M
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_548259
359
40831
S294
H
L
D
Y
N
S
D
S
P
L
L
P
K
M
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8VC48
359
40614
S294
H
L
D
Y
N
S
D
S
P
L
L
P
K
M
K
Rat
Rattus norvegicus
O88177
359
40663
S294
H
L
D
Y
N
S
D
S
P
L
L
P
K
M
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511496
312
33803
E248
L
P
L
V
P
F
P
E
R
R
L
C
P
E
K
Chicken
Gallus gallus
XP_415773
356
39947
S291
H
L
D
H
G
V
D
S
A
L
L
P
K
L
K
Frog
Xenopus laevis
NP_001086511
353
40718
P289
F
D
L
E
T
Y
S
P
L
L
P
K
L
R
T
Zebra Danio
Brachydanio rerio
NP_956499
303
34092
V239
A
A
V
G
G
V
A
V
S
L
S
T
S
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VPT5
297
34525
E233
P
R
K
Q
L
P
K
E
V
Q
Q
S
L
P
Q
Honey Bee
Apis mellifera
XP_624974
285
32991
I221
P
I
P
S
P
P
K
I
P
E
I
A
K
Q
Y
Nematode Worm
Caenorhab. elegans
Q19189
359
41271
I293
P
S
P
P
H
K
M
I
I
S
E
S
E
I
L
Sea Urchin
Strong. purpuratus
XP_788130
354
40571
Q289
E
R
E
P
E
Y
C
Q
I
L
L
P
R
D
V
Poplar Tree
Populus trichocarpa
XP_002325774
388
43941
G324
A
P
K
V
A
K
E
G
I
P
L
P
P
D
R
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M841
393
44382
G329
A
P
K
M
A
K
E
G
I
P
L
P
P
D
R
Baker's Yeast
Sacchar. cerevisiae
Q04370
399
45974
T324
F
S
S
H
S
D
K
T
E
D
K
E
G
V
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
N.A.
92.1
N.A.
89.4
88.5
N.A.
46.7
76
64
51.5
N.A.
29.8
31.7
35.9
45.6
Protein Similarity:
100
99.7
N.A.
96
N.A.
93.3
92.7
N.A.
57.3
85.7
79.6
65.4
N.A.
47
49
56.2
68.5
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
13.3
66.6
6.6
6.6
N.A.
0
13.3
0
20
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
13.3
80
6.6
13.3
N.A.
6.6
26.6
20
33.3
Percent
Protein Identity:
31.9
N.A.
N.A.
31.3
22.3
N.A.
Protein Similarity:
48.7
N.A.
N.A.
48.3
40.3
N.A.
P-Site Identity:
13.3
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
26.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
7
0
0
13
0
7
0
7
0
0
7
0
0
0
% A
% Cys:
0
0
0
0
0
0
7
0
0
0
0
7
0
0
0
% C
% Asp:
0
7
38
0
0
7
38
0
0
7
0
0
0
19
0
% D
% Glu:
7
0
7
7
7
0
13
13
7
7
7
7
7
7
0
% E
% Phe:
13
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
7
13
0
0
13
0
0
0
0
7
0
0
% G
% His:
38
0
0
13
7
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
7
0
0
0
0
0
13
25
0
7
0
0
7
0
% I
% Lys:
0
0
19
0
0
19
19
0
0
0
7
7
44
0
44
% K
% Leu:
7
38
13
0
7
0
0
0
7
57
63
0
13
13
7
% L
% Met:
0
0
0
7
0
0
7
0
0
0
0
0
0
32
0
% M
% Asn:
0
0
0
0
32
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
19
19
13
13
13
13
7
7
38
13
7
57
19
7
0
% P
% Gln:
0
0
0
7
0
0
0
7
0
7
7
0
0
7
7
% Q
% Arg:
0
13
0
0
0
0
0
0
7
7
0
0
7
7
13
% R
% Ser:
0
13
7
7
7
32
7
38
7
7
7
13
7
0
13
% S
% Thr:
0
0
0
0
7
0
0
7
0
0
0
7
0
0
7
% T
% Val:
0
0
7
13
0
13
0
7
7
0
0
0
0
7
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
32
0
13
0
0
0
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _