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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PEX12
All Species:
22.42
Human Site:
S234
Identified Species:
32.89
UniProt:
O00623
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00623
NP_000277.1
359
40797
S234
S
V
S
E
K
I
N
S
A
L
K
K
A
V
G
Chimpanzee
Pan troglodytes
XP_001174172
359
40821
S234
S
V
S
E
K
I
K
S
A
L
K
K
A
V
G
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_548259
359
40831
S234
S
V
G
D
K
I
K
S
S
L
K
K
A
L
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8VC48
359
40614
S234
S
V
G
E
K
I
K
S
A
L
K
K
A
V
G
Rat
Rattus norvegicus
O88177
359
40663
S234
S
I
G
K
K
I
K
S
A
L
K
K
A
V
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511496
312
33803
R188
Y
T
L
G
W
A
E
R
H
S
P
L
L
G
L
Chicken
Gallus gallus
XP_415773
356
39947
S231
S
I
K
T
Q
V
Q
S
A
V
R
K
A
L
G
Frog
Xenopus laevis
NP_001086511
353
40718
I229
I
S
Q
H
I
R
S
I
L
K
K
A
L
G
A
Zebra Danio
Brachydanio rerio
NP_956499
303
34092
F179
C
Q
Q
L
L
Y
V
F
G
K
T
R
T
H
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VPT5
297
34525
L173
F
R
L
L
G
L
T
L
R
Y
P
S
E
P
P
Honey Bee
Apis mellifera
XP_624974
285
32991
D161
K
P
I
L
S
I
S
D
F
L
K
K
I
R
T
Nematode Worm
Caenorhab. elegans
Q19189
359
41271
H233
G
T
L
N
E
H
I
H
L
R
F
F
N
R
I
Sea Urchin
Strong. purpuratus
XP_788130
354
40571
Y229
S
L
K
A
R
L
L
Y
Y
L
K
R
L
V
G
Poplar Tree
Populus trichocarpa
XP_002325774
388
43941
Q264
P
P
W
L
K
A
L
Q
G
A
L
L
S
C
G
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M841
393
44382
Q269
P
P
W
L
K
T
V
Q
G
A
L
L
S
C
S
Baker's Yeast
Sacchar. cerevisiae
Q04370
399
45974
L264
F
A
L
M
Q
G
Q
L
S
I
I
P
R
F
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
N.A.
92.1
N.A.
89.4
88.5
N.A.
46.7
76
64
51.5
N.A.
29.8
31.7
35.9
45.6
Protein Similarity:
100
99.7
N.A.
96
N.A.
93.3
92.7
N.A.
57.3
85.7
79.6
65.4
N.A.
47
49
56.2
68.5
P-Site Identity:
100
93.3
N.A.
66.6
N.A.
86.6
73.3
N.A.
0
40
6.6
0
N.A.
0
26.6
0
33.3
P-Site Similarity:
100
93.3
N.A.
86.6
N.A.
86.6
86.6
N.A.
0
80
13.3
6.6
N.A.
6.6
33.3
6.6
60
Percent
Protein Identity:
31.9
N.A.
N.A.
31.3
22.3
N.A.
Protein Similarity:
48.7
N.A.
N.A.
48.3
40.3
N.A.
P-Site Identity:
13.3
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
20
N.A.
N.A.
13.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
7
0
13
0
0
32
13
0
7
38
0
7
% A
% Cys:
7
0
0
0
0
0
0
0
0
0
0
0
0
13
0
% C
% Asp:
0
0
0
7
0
0
0
7
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
19
7
0
7
0
0
0
0
0
7
0
0
% E
% Phe:
13
0
0
0
0
0
0
7
7
0
7
7
0
7
0
% F
% Gly:
7
0
19
7
7
7
0
0
19
0
0
0
0
13
50
% G
% His:
0
0
0
7
0
7
0
7
7
0
0
0
0
7
0
% H
% Ile:
7
13
7
0
7
38
7
7
0
7
7
0
7
0
7
% I
% Lys:
7
0
13
7
44
0
25
0
0
13
50
44
0
0
0
% K
% Leu:
0
7
25
32
7
13
13
13
13
44
13
19
19
13
13
% L
% Met:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
7
0
0
7
0
0
0
0
0
7
0
0
% N
% Pro:
13
19
0
0
0
0
0
0
0
0
13
7
0
7
7
% P
% Gln:
0
7
13
0
13
0
13
13
0
0
0
0
0
0
0
% Q
% Arg:
0
7
0
0
7
7
0
7
7
7
7
13
7
13
0
% R
% Ser:
44
7
13
0
7
0
13
38
13
7
0
7
13
0
13
% S
% Thr:
0
13
0
7
0
7
7
0
0
0
7
0
7
0
7
% T
% Val:
0
25
0
0
0
7
13
0
0
7
0
0
0
32
0
% V
% Trp:
0
0
13
0
7
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
7
0
7
7
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _