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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PEX12
All Species:
20
Human Site:
S105
Identified Species:
29.33
UniProt:
O00623
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00623
NP_000277.1
359
40797
S105
H
K
S
Q
R
L
A
S
A
G
L
P
K
Q
Q
Chimpanzee
Pan troglodytes
XP_001174172
359
40821
S105
H
K
S
Q
R
L
A
S
A
G
L
P
K
Q
Q
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_548259
359
40831
S105
H
K
L
E
R
L
A
S
A
G
L
P
K
K
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8VC48
359
40614
S105
P
H
L
Q
R
P
A
S
A
G
L
P
K
E
H
Rat
Rattus norvegicus
O88177
359
40663
S105
P
Q
L
Q
R
P
A
S
A
G
L
P
K
E
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511496
312
33803
E62
F
L
W
R
W
F
D
E
L
F
A
L
L
D
L
Chicken
Gallus gallus
XP_415773
356
39947
T104
C
K
Q
Q
P
L
A
T
A
G
L
P
K
K
Q
Frog
Xenopus laevis
NP_001086511
353
40718
L103
K
Q
V
G
Q
R
N
L
A
R
K
E
Y
W
K
Zebra Danio
Brachydanio rerio
NP_956499
303
34092
Y52
A
T
S
N
P
A
R
Y
G
V
L
W
R
R
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VPT5
297
34525
F47
Y
F
G
L
R
L
D
F
K
L
W
G
S
L
R
Honey Bee
Apis mellifera
XP_624974
285
32991
F35
A
H
T
V
E
P
A
F
T
K
F
L
S
F
I
Nematode Worm
Caenorhab. elegans
Q19189
359
41271
N106
S
G
T
G
N
P
P
N
D
G
R
E
R
I
M
Sea Urchin
Strong. purpuratus
XP_788130
354
40571
I103
S
T
S
A
A
P
S
I
S
E
G
L
P
K
R
Poplar Tree
Populus trichocarpa
XP_002325774
388
43941
H106
N
S
G
D
G
I
Q
H
S
G
L
E
K
H
Q
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M841
393
44382
H106
D
S
S
E
E
V
Q
H
S
G
L
E
K
R
Q
Baker's Yeast
Sacchar. cerevisiae
Q04370
399
45974
L121
N
L
A
L
T
Q
C
L
N
P
K
G
Q
S
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
N.A.
92.1
N.A.
89.4
88.5
N.A.
46.7
76
64
51.5
N.A.
29.8
31.7
35.9
45.6
Protein Similarity:
100
99.7
N.A.
96
N.A.
93.3
92.7
N.A.
57.3
85.7
79.6
65.4
N.A.
47
49
56.2
68.5
P-Site Identity:
100
100
N.A.
80
N.A.
60
60
N.A.
0
66.6
6.6
13.3
N.A.
13.3
6.6
6.6
6.6
P-Site Similarity:
100
100
N.A.
93.3
N.A.
66.6
73.3
N.A.
6.6
80
26.6
26.6
N.A.
26.6
13.3
26.6
33.3
Percent
Protein Identity:
31.9
N.A.
N.A.
31.3
22.3
N.A.
Protein Similarity:
48.7
N.A.
N.A.
48.3
40.3
N.A.
P-Site Identity:
26.6
N.A.
N.A.
33.3
0
N.A.
P-Site Similarity:
46.6
N.A.
N.A.
60
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
0
7
7
7
7
44
0
44
0
7
0
0
0
0
% A
% Cys:
7
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
0
7
0
0
13
0
7
0
0
0
0
7
0
% D
% Glu:
0
0
0
13
13
0
0
7
0
7
0
25
0
13
7
% E
% Phe:
7
7
0
0
0
7
0
13
0
7
7
0
0
7
7
% F
% Gly:
0
7
13
13
7
0
0
0
7
57
7
13
0
0
0
% G
% His:
19
13
0
0
0
0
0
13
0
0
0
0
0
7
13
% H
% Ile:
0
0
0
0
0
7
0
7
0
0
0
0
0
7
7
% I
% Lys:
7
25
0
0
0
0
0
0
7
7
13
0
50
19
7
% K
% Leu:
0
13
19
13
0
32
0
13
7
7
57
19
7
7
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% M
% Asn:
13
0
0
7
7
0
7
7
7
0
0
0
0
0
0
% N
% Pro:
13
0
0
0
13
32
7
0
0
7
0
38
7
0
0
% P
% Gln:
0
13
7
32
7
7
13
0
0
0
0
0
7
13
38
% Q
% Arg:
0
0
0
7
38
7
7
0
0
7
7
0
13
13
13
% R
% Ser:
13
13
32
0
0
0
7
32
19
0
0
0
13
7
0
% S
% Thr:
0
13
13
0
7
0
0
7
7
0
0
0
0
0
0
% T
% Val:
0
0
7
7
0
7
0
0
0
7
0
0
0
0
0
% V
% Trp:
0
0
7
0
7
0
0
0
0
0
7
7
0
7
0
% W
% Tyr:
7
0
0
0
0
0
0
7
0
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _