KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYR61
All Species:
31.52
Human Site:
S95
Identified Species:
86.67
UniProt:
O00622
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00622
NP_001545.2
381
42027
S95
K
G
I
C
R
A
Q
S
E
G
R
P
C
E
Y
Chimpanzee
Pan troglodytes
A5A6L1
381
41994
S95
K
G
I
C
R
A
Q
S
E
G
R
P
C
E
Y
Rhesus Macaque
Macaca mulatta
XP_001104992
386
42897
S100
K
G
I
C
R
A
Q
S
E
G
R
P
C
E
Y
Dog
Lupus familis
XP_537091
381
41751
S95
K
G
I
C
R
A
Q
S
E
G
R
P
C
E
Y
Cat
Felis silvestris
Mouse
Mus musculus
P18406
379
41690
S95
K
G
I
C
R
A
Q
S
E
G
R
P
C
E
Y
Rat
Rattus norvegicus
Q9ES72
379
41668
S95
K
G
I
C
R
A
Q
S
E
G
R
P
C
E
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518019
382
41865
S95
K
G
I
C
R
A
Q
S
E
G
R
P
C
E
Y
Chicken
Gallus gallus
P19336
375
40633
S95
N
G
I
C
R
A
Q
S
E
G
R
P
C
E
Y
Frog
Xenopus laevis
P51609
343
38052
D69
H
L
N
P
C
Q
E
D
K
G
L
Y
C
E
F
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
90.1
94.2
N.A.
92.1
91.8
N.A.
84.8
81.3
42.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
100
91.1
95.2
N.A.
94.4
94.2
N.A.
89.5
86.8
56.1
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
93.3
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
93.3
40
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
89
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
89
12
0
0
0
0
0
0
0
100
0
0
% C
% Asp:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
12
0
89
0
0
0
0
100
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% F
% Gly:
0
89
0
0
0
0
0
0
0
100
0
0
0
0
0
% G
% His:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
89
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
78
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% K
% Leu:
0
12
0
0
0
0
0
0
0
0
12
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
12
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
12
0
0
0
0
0
0
0
89
0
0
0
% P
% Gln:
0
0
0
0
0
12
89
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
89
0
0
0
0
0
89
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
89
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
89
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _