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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CXCR6
All Species:
8.48
Human Site:
T146
Identified Species:
20.74
UniProt:
O00574
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00574
NP_006555.1
342
39280
T146
N
Q
Q
A
K
R
M
T
W
G
K
V
T
S
L
Chimpanzee
Pan troglodytes
Q9TV16
342
39255
T146
N
Q
Q
A
K
R
M
T
W
G
K
V
T
S
L
Rhesus Macaque
Macaca mulatta
Q9XT45
343
39405
T147
N
Q
Q
A
K
R
M
T
W
G
K
V
I
C
L
Dog
Lupus familis
XP_851891
341
39131
A145
N
Q
Q
A
K
R
M
A
W
G
K
A
I
C
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQ16
351
40449
I155
N
R
Q
A
K
W
K
I
W
G
Q
V
I
C
L
Rat
Rattus norvegicus
O08565
349
39316
E150
S
A
R
K
L
L
A
E
K
A
V
Y
V
G
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513641
446
50070
V240
S
W
K
Q
K
R
V
V
Y
S
K
V
I
C
L
Chicken
Gallus gallus
NP_001039305
382
43412
C159
I
L
R
S
K
V
V
C
F
A
V
W
L
A
S
Frog
Xenopus laevis
Q7ZXJ7
358
40009
D157
G
S
R
K
M
L
A
D
K
V
V
Y
A
G
V
Zebra Danio
Brachydanio rerio
XP_001343888
425
48481
L220
N
S
K
R
S
R
L
L
Y
S
K
L
I
C
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
94.7
81.5
N.A.
74
31.5
N.A.
30.2
33.7
31.8
33.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
97.3
90.3
N.A.
84.3
56.7
N.A.
47.9
55.5
56.4
55.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
86.6
73.3
N.A.
53.3
0
N.A.
33.3
6.6
0
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
86.6
73.3
N.A.
66.6
20
N.A.
60
40
13.3
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
50
0
0
20
10
0
20
0
10
10
10
0
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
0
0
50
0
% C
% Asp:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% F
% Gly:
10
0
0
0
0
0
0
0
0
50
0
0
0
20
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
0
10
0
0
0
0
50
0
0
% I
% Lys:
0
0
20
20
70
0
10
0
20
0
60
0
0
0
0
% K
% Leu:
0
10
0
0
10
20
10
10
0
0
0
10
10
0
60
% L
% Met:
0
0
0
0
10
0
40
0
0
0
0
0
0
0
0
% M
% Asn:
60
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
40
50
10
0
0
0
0
0
0
10
0
0
0
0
% Q
% Arg:
0
10
30
10
0
60
0
0
0
0
0
0
0
0
0
% R
% Ser:
20
20
0
10
10
0
0
0
0
20
0
0
0
20
10
% S
% Thr:
0
0
0
0
0
0
0
30
0
0
0
0
20
0
0
% T
% Val:
0
0
0
0
0
10
20
10
0
10
30
50
10
0
30
% V
% Trp:
0
10
0
0
0
10
0
0
50
0
0
10
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
20
0
0
20
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _