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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CXCR6 All Species: 15.76
Human Site: S315 Identified Species: 38.52
UniProt: O00574 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00574 NP_006555.1 342 39280 S315 C L P Y L G V S H Q W K S S E
Chimpanzee Pan troglodytes Q9TV16 342 39255 S315 C L P Y L G V S H Q W K S S E
Rhesus Macaque Macaca mulatta Q9XT45 343 39405 S316 C L P Y L G V S H Q W K S S E
Dog Lupus familis XP_851891 341 39131 L314 C L P Y L G V L G Q W K S S E
Cat Felis silvestris
Mouse Mus musculus Q9EQ16 351 40449 S324 C L S H L G V S S Q W K S S E
Rat Rattus norvegicus O08565 349 39316 S322 N S M S R G S S L K I L S K G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513641 446 50070 C419 K V L K K L G C I R K T S T W
Chicken Gallus gallus NP_001039305 382 43412 L354 S N W S F A M L G R R R V R N
Frog Xenopus laevis Q7ZXJ7 358 40009 S332 T S V S R G S S L K I L S K K
Zebra Danio Brachydanio rerio XP_001343888 425 48481 V396 I F Q N I G C V S N L K N S K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 94.7 81.5 N.A. 74 31.5 N.A. 30.2 33.7 31.8 33.1 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.7 97.3 90.3 N.A. 84.3 56.7 N.A. 47.9 55.5 56.4 55.5 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 86.6 N.A. 80 20 N.A. 6.6 0 20 20 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 86.6 N.A. 86.6 26.6 N.A. 26.6 20 33.3 40 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % A
% Cys: 50 0 0 0 0 0 10 10 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 50 % E
% Phe: 0 10 0 0 10 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 80 10 0 20 0 0 0 0 0 10 % G
% His: 0 0 0 10 0 0 0 0 30 0 0 0 0 0 0 % H
% Ile: 10 0 0 0 10 0 0 0 10 0 20 0 0 0 0 % I
% Lys: 10 0 0 10 10 0 0 0 0 20 10 60 0 20 20 % K
% Leu: 0 50 10 0 50 10 0 20 20 0 10 20 0 0 0 % L
% Met: 0 0 10 0 0 0 10 0 0 0 0 0 0 0 0 % M
% Asn: 10 10 0 10 0 0 0 0 0 10 0 0 10 0 10 % N
% Pro: 0 0 40 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 10 0 0 0 0 0 0 50 0 0 0 0 0 % Q
% Arg: 0 0 0 0 20 0 0 0 0 20 10 10 0 10 0 % R
% Ser: 10 20 10 30 0 0 20 60 20 0 0 0 80 60 0 % S
% Thr: 10 0 0 0 0 0 0 0 0 0 0 10 0 10 0 % T
% Val: 0 10 10 0 0 0 50 10 0 0 0 0 10 0 0 % V
% Trp: 0 0 10 0 0 0 0 0 0 0 50 0 0 0 10 % W
% Tyr: 0 0 0 40 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _