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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NOP56
All Species:
10.61
Human Site:
T543
Identified Species:
16.67
UniProt:
O00567
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.36
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00567
NP_006383.2
594
66050
T543
K
S
T
P
K
E
E
T
V
N
D
P
E
E
A
Chimpanzee
Pan troglodytes
XP_514472
779
85531
T728
R
S
T
P
E
E
E
T
V
N
D
P
E
E
A
Rhesus Macaque
Macaca mulatta
XP_001110561
587
65499
T536
K
S
S
P
K
E
E
T
V
N
D
P
E
E
A
Dog
Lupus familis
XP_851724
597
66425
P543
K
S
F
P
K
E
E
P
V
S
D
A
E
E
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9D6Z1
580
64446
P530
A
K
R
K
K
S
S
P
K
E
E
V
A
S
E
Rat
Rattus norvegicus
Q9QZ86
534
60052
V483
E
A
E
E
E
Q
V
V
E
E
E
P
T
V
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026559
535
59815
K482
N
I
E
P
K
K
K
K
K
K
K
K
E
Q
E
Frog
Xenopus laevis
NP_001082151
532
59707
K482
E
E
D
E
E
P
K
K
K
K
K
K
R
H
S
Zebra Danio
Brachydanio rerio
Q7SXM7
508
56455
G458
T
V
R
D
R
S
S
G
T
S
S
S
V
A
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651040
496
54819
K446
S
E
K
K
K
K
K
K
K
R
A
A
E
D
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q21276
486
54493
E436
E
A
E
E
A
A
V
E
V
K
E
K
V
I
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002318715
540
60255
K488
A
K
S
E
K
K
R
K
K
E
K
R
K
L
E
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9MAB3
533
58985
K483
P
S
E
K
K
K
K
K
K
A
E
A
E
T
E
Baker's Yeast
Sacchar. cerevisiae
Q12460
504
56846
K454
T
K
E
K
E
S
S
K
K
R
K
L
E
D
D
Red Bread Mold
Neurospora crassa
Q8X066
597
66063
S531
R
F
E
R
G
Q
I
S
I
K
E
D
G
T
L
Conservation
Percent
Protein Identity:
100
75.3
89.5
94.1
N.A.
89.9
38.2
N.A.
N.A.
71.5
70.1
20.5
N.A.
54.5
N.A.
48.9
N.A.
Protein Similarity:
100
75.8
92.2
96.3
N.A.
92.9
56.7
N.A.
N.A.
80.3
79.6
40.5
N.A.
66.5
N.A.
61.9
N.A.
P-Site Identity:
100
86.6
93.3
73.3
N.A.
6.6
6.6
N.A.
N.A.
20
0
0
N.A.
13.3
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
80
N.A.
13.3
40
N.A.
N.A.
40
26.6
13.3
N.A.
33.3
N.A.
26.6
N.A.
Percent
Protein Identity:
50.8
N.A.
N.A.
39
46.3
35
Protein Similarity:
66.1
N.A.
N.A.
57.4
61.7
52.7
P-Site Identity:
6.6
N.A.
N.A.
20
6.6
0
P-Site Similarity:
26.6
N.A.
N.A.
40
20
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
14
0
0
7
7
0
0
0
7
7
20
7
7
27
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
7
7
0
0
0
0
0
0
27
7
0
14
7
% D
% Glu:
20
14
40
27
27
27
27
7
7
20
34
0
54
27
34
% E
% Phe:
0
7
7
0
0
0
0
0
0
0
0
0
0
0
7
% F
% Gly:
0
0
0
0
7
0
0
7
0
0
0
0
7
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% H
% Ile:
0
7
0
0
0
0
7
0
7
0
0
0
0
7
0
% I
% Lys:
20
20
7
27
54
27
27
40
47
27
27
20
7
0
14
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
7
0
7
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
7
0
0
0
0
0
0
0
0
20
0
0
0
0
0
% N
% Pro:
7
0
0
34
0
7
0
14
0
0
0
27
0
0
0
% P
% Gln:
0
0
0
0
0
14
0
0
0
0
0
0
0
7
0
% Q
% Arg:
14
0
14
7
7
0
7
0
0
14
0
7
7
0
0
% R
% Ser:
7
34
14
0
0
20
20
7
0
14
7
7
0
7
7
% S
% Thr:
14
0
14
0
0
0
0
20
7
0
0
0
7
14
0
% T
% Val:
0
7
0
0
0
0
14
7
34
0
0
7
14
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _