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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NOP56
All Species:
13.94
Human Site:
S519
Identified Species:
21.9
UniProt:
O00567
Number Species:
14
Phosphosite Substitution
Charge Score:
0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00567
NP_006383.2
594
66050
S519
F
S
K
E
E
L
M
S
S
D
L
E
E
T
A
Chimpanzee
Pan troglodytes
XP_514472
779
85531
S704
F
S
K
E
E
L
M
S
S
D
L
E
E
T
A
Rhesus Macaque
Macaca mulatta
XP_001110561
587
65499
S512
F
S
K
E
E
L
M
S
S
D
L
E
E
T
A
Dog
Lupus familis
XP_851724
597
66425
S519
F
S
K
E
E
L
V
S
S
D
V
E
E
T
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9D6Z1
580
64446
A506
P
K
S
K
K
K
K
A
P
K
E
E
L
A
S
Rat
Rattus norvegicus
Q9QZ86
534
60052
A459
D
E
I
T
E
K
K
A
K
K
A
K
I
K
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026559
535
59815
A458
K
R
R
L
E
A
Q
A
A
A
A
E
E
M
E
Frog
Xenopus laevis
NP_001082151
532
59707
A458
K
R
Q
L
E
A
L
A
A
E
E
A
E
E
P
Zebra Danio
Brachydanio rerio
Q7SXM7
508
56455
S434
T
K
A
R
I
S
K
S
L
Q
R
T
L
Q
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651040
496
54819
M422
P
R
K
N
I
E
V
M
K
E
A
I
E
A
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q21276
486
54493
E412
Q
Q
V
E
D
R
L
E
Y
F
T
S
G
T
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002318715
540
60255
N464
S
K
S
D
T
A
E
N
G
E
A
E
D
K
P
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9MAB3
533
58985
D459
E
E
P
S
K
K
K
D
K
K
K
K
K
K
V
Baker's Yeast
Sacchar. cerevisiae
Q12460
504
56846
E430
K
N
E
L
A
I
Q
E
A
M
E
L
Y
N
K
Red Bread Mold
Neurospora crassa
Q8X066
597
66063
F507
K
E
L
D
D
E
D
F
E
R
L
A
K
A
A
Conservation
Percent
Protein Identity:
100
75.3
89.5
94.1
N.A.
89.9
38.2
N.A.
N.A.
71.5
70.1
20.5
N.A.
54.5
N.A.
48.9
N.A.
Protein Similarity:
100
75.8
92.2
96.3
N.A.
92.9
56.7
N.A.
N.A.
80.3
79.6
40.5
N.A.
66.5
N.A.
61.9
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
6.6
6.6
N.A.
N.A.
20
13.3
6.6
N.A.
20
N.A.
13.3
N.A.
P-Site Similarity:
100
100
100
100
N.A.
33.3
20
N.A.
N.A.
40
46.6
6.6
N.A.
33.3
N.A.
26.6
N.A.
Percent
Protein Identity:
50.8
N.A.
N.A.
39
46.3
35
Protein Similarity:
66.1
N.A.
N.A.
57.4
61.7
52.7
P-Site Identity:
6.6
N.A.
N.A.
0
0
13.3
P-Site Similarity:
33.3
N.A.
N.A.
20
26.6
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
7
20
0
27
20
7
27
14
0
20
40
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
0
14
14
0
7
7
0
27
0
0
7
0
0
% D
% Glu:
7
20
7
34
47
14
7
14
7
20
20
47
47
7
7
% E
% Phe:
27
0
0
0
0
0
0
7
0
7
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
7
0
0
0
7
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
7
0
14
7
0
0
0
0
0
7
7
0
7
% I
% Lys:
27
20
34
7
14
20
27
0
20
20
7
14
14
20
14
% K
% Leu:
0
0
7
20
0
27
14
0
7
0
27
7
14
0
0
% L
% Met:
0
0
0
0
0
0
20
7
0
7
0
0
0
7
0
% M
% Asn:
0
7
0
7
0
0
0
7
0
0
0
0
0
7
0
% N
% Pro:
14
0
7
0
0
0
0
0
7
0
0
0
0
0
14
% P
% Gln:
7
7
7
0
0
0
14
0
0
7
0
0
0
7
0
% Q
% Arg:
0
20
7
7
0
7
0
0
0
7
7
0
0
0
0
% R
% Ser:
7
27
14
7
0
7
0
34
27
0
0
7
0
0
7
% S
% Thr:
7
0
0
7
7
0
0
0
0
0
7
7
0
34
0
% T
% Val:
0
0
7
0
0
0
14
0
0
0
7
0
0
0
14
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
7
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _