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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MPHOSPH10
All Species:
37.27
Human Site:
Y454
Identified Species:
63.08
UniProt:
O00566
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00566
NP_005782.1
681
78864
Y454
P
K
E
D
A
Y
E
Y
K
K
R
L
T
L
D
Chimpanzee
Pan troglodytes
XP_515539
681
78871
Y454
P
K
E
D
A
Y
E
Y
K
K
R
L
T
L
D
Rhesus Macaque
Macaca mulatta
XP_001102757
682
78836
Y455
P
K
E
D
A
Y
E
Y
K
K
R
L
T
L
D
Dog
Lupus familis
XP_849351
676
78277
Y449
P
K
E
D
A
Y
E
Y
K
K
R
L
T
L
D
Cat
Felis silvestris
Mouse
Mus musculus
Q810V0
681
78656
Y455
P
K
E
D
A
Y
E
Y
K
K
R
L
T
L
D
Rat
Rattus norvegicus
NP_001099810
676
77809
Y450
P
K
E
D
A
Y
E
Y
K
K
R
L
T
L
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509780
472
52873
L261
H
E
K
S
K
L
S
L
A
E
I
Y
E
Q
E
Chicken
Gallus gallus
XP_413769
665
76446
Y438
P
K
E
D
A
F
E
Y
K
K
R
I
T
L
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_709654
695
79706
Y464
P
K
E
E
V
F
E
Y
K
K
R
L
T
L
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609237
662
76083
Y434
P
V
N
T
P
Q
E
Y
R
K
Q
L
V
L
D
Honey Bee
Apis mellifera
XP_394707
639
74546
Y409
P
V
E
T
P
L
E
Y
K
K
K
L
I
L
N
Nematode Worm
Caenorhab. elegans
NP_499580
648
73878
F430
V
E
A
K
G
A
K
F
E
T
E
A
I
E
N
Sea Urchin
Strong. purpuratus
XP_798175
686
78053
F459
P
K
E
E
A
K
E
F
K
K
R
V
T
L
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P47083
593
66934
Q382
D
S
N
F
D
D
L
Q
R
R
T
L
L
D
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
96.3
86.1
N.A.
82.6
80.6
N.A.
43.7
61.2
N.A.
56.5
N.A.
35
43.6
32.7
41.1
Protein Similarity:
100
99.2
98.3
93.8
N.A.
90.7
89.4
N.A.
53.8
77.6
N.A.
71.8
N.A.
54.3
61.8
53.2
59.9
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
0
86.6
N.A.
80
N.A.
46.6
53.3
0
73.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
26.6
100
N.A.
93.3
N.A.
60
66.6
33.3
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
58
8
0
0
8
0
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
50
8
8
0
0
0
0
0
0
0
8
72
% D
% Glu:
0
15
72
15
0
0
79
0
8
8
8
0
8
8
8
% E
% Phe:
0
0
0
8
0
15
0
15
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
8
8
15
0
8
% I
% Lys:
0
65
8
8
8
8
8
0
72
79
8
0
0
0
0
% K
% Leu:
0
0
0
0
0
15
8
8
0
0
0
72
8
79
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
15
0
0
0
0
0
0
0
0
0
0
0
15
% N
% Pro:
79
0
0
0
15
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
8
0
8
0
0
8
0
0
8
0
% Q
% Arg:
0
0
0
0
0
0
0
0
15
8
65
0
0
0
0
% R
% Ser:
0
8
0
8
0
0
8
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
15
0
0
0
0
0
8
8
0
65
0
0
% T
% Val:
8
15
0
0
8
0
0
0
0
0
0
8
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
43
0
72
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _