KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MPHOSPH10
All Species:
22.73
Human Site:
Y452
Identified Species:
38.46
UniProt:
O00566
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00566
NP_005782.1
681
78864
Y452
E
K
P
K
E
D
A
Y
E
Y
K
K
R
L
T
Chimpanzee
Pan troglodytes
XP_515539
681
78871
Y452
E
K
P
K
E
D
A
Y
E
Y
K
K
R
L
T
Rhesus Macaque
Macaca mulatta
XP_001102757
682
78836
Y453
E
K
P
K
E
D
A
Y
E
Y
K
K
R
L
T
Dog
Lupus familis
XP_849351
676
78277
Y447
E
K
P
K
E
D
A
Y
E
Y
K
K
R
L
T
Cat
Felis silvestris
Mouse
Mus musculus
Q810V0
681
78656
Y453
E
K
P
K
E
D
A
Y
E
Y
K
K
R
L
T
Rat
Rattus norvegicus
NP_001099810
676
77809
Y448
E
K
P
K
E
D
A
Y
E
Y
K
K
R
L
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509780
472
52873
L259
L
D
H
E
K
S
K
L
S
L
A
E
I
Y
E
Chicken
Gallus gallus
XP_413769
665
76446
F436
E
R
P
K
E
D
A
F
E
Y
K
K
R
I
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_709654
695
79706
F462
E
K
P
K
E
E
V
F
E
Y
K
K
R
L
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609237
662
76083
Q432
V
R
P
V
N
T
P
Q
E
Y
R
K
Q
L
V
Honey Bee
Apis mellifera
XP_394707
639
74546
L407
F
K
P
V
E
T
P
L
E
Y
K
K
K
L
I
Nematode Worm
Caenorhab. elegans
NP_499580
648
73878
A428
K
K
V
E
A
K
G
A
K
F
E
T
E
A
I
Sea Urchin
Strong. purpuratus
XP_798175
686
78053
K457
A
K
P
K
E
E
A
K
E
F
K
K
R
V
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P47083
593
66934
D380
I
Q
D
S
N
F
D
D
L
Q
R
R
T
L
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
96.3
86.1
N.A.
82.6
80.6
N.A.
43.7
61.2
N.A.
56.5
N.A.
35
43.6
32.7
41.1
Protein Similarity:
100
99.2
98.3
93.8
N.A.
90.7
89.4
N.A.
53.8
77.6
N.A.
71.8
N.A.
54.3
61.8
53.2
59.9
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
0
80
N.A.
80
N.A.
33.3
53.3
6.6
66.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
20
100
N.A.
93.3
N.A.
53.3
60
40
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
8
0
58
8
0
0
8
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
8
0
0
50
8
8
0
0
0
0
0
0
0
% D
% Glu:
58
0
0
15
72
15
0
0
79
0
8
8
8
0
8
% E
% Phe:
8
0
0
0
0
8
0
15
0
15
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
0
0
0
0
0
0
0
8
8
15
% I
% Lys:
8
72
0
65
8
8
8
8
8
0
72
79
8
0
0
% K
% Leu:
8
0
0
0
0
0
0
15
8
8
0
0
0
72
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
15
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
79
0
0
0
15
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
0
0
0
0
8
0
8
0
0
8
0
0
% Q
% Arg:
0
15
0
0
0
0
0
0
0
0
15
8
65
0
0
% R
% Ser:
0
0
0
8
0
8
0
0
8
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
15
0
0
0
0
0
8
8
0
65
% T
% Val:
8
0
8
15
0
0
8
0
0
0
0
0
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
43
0
72
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _