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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MPHOSPH10 All Species: 17.88
Human Site: S257 Identified Species: 30.26
UniProt: O00566 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00566 NP_005782.1 681 78864 S257 F G S K K L K S G K S S R N L
Chimpanzee Pan troglodytes XP_515539 681 78871 S257 F G S K K L K S G K S S R N L
Rhesus Macaque Macaca mulatta XP_001102757 682 78836 S258 F G S K K L K S G K S S R N L
Dog Lupus familis XP_849351 676 78277 S256 F G S Q K P K S G K S S R N L
Cat Felis silvestris
Mouse Mus musculus Q810V0 681 78656 S259 F G R Q K I K S N K S S R N L
Rat Rattus norvegicus NP_001099810 676 77809 K256 G G L F G K Q K I K S N K S S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509780 472 52873 P86 S W R G G E G P H E E R G R G
Chicken Gallus gallus XP_413769 665 76446 F240 S E D E E E E F E E A K V K P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_709654 695 79706 K258 P V V K K K L K N K S S R N M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_609237 662 76083 H241 M N E E L T E H S K K I N K G
Honey Bee Apis mellifera XP_394707 639 74546 N230 S P E S E D E N L D N S I Q H
Nematode Worm Caenorhab. elegans NP_499580 648 73878 D233 F E D E D S W D G K T D Y T Y
Sea Urchin Strong. purpuratus XP_798175 686 78053 D253 D D D E E K Q D N K S T R D M
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P47083 593 66934 S207 A E D S N E A S E G S E D E D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 96.3 86.1 N.A. 82.6 80.6 N.A. 43.7 61.2 N.A. 56.5 N.A. 35 43.6 32.7 41.1
Protein Similarity: 100 99.2 98.3 93.8 N.A. 90.7 89.4 N.A. 53.8 77.6 N.A. 71.8 N.A. 54.3 61.8 53.2 59.9
P-Site Identity: 100 100 100 86.6 N.A. 73.3 20 N.A. 0 0 N.A. 46.6 N.A. 6.6 6.6 20 20
P-Site Similarity: 100 100 100 93.3 N.A. 86.6 46.6 N.A. 6.6 33.3 N.A. 53.3 N.A. 20 33.3 33.3 60
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.1 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 46.8 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 0 0 8 0 0 0 8 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 8 29 0 8 8 0 15 0 8 0 8 8 8 8 % D
% Glu: 0 22 15 29 22 22 22 0 15 15 8 8 0 8 0 % E
% Phe: 43 0 0 8 0 0 0 8 0 0 0 0 0 0 0 % F
% Gly: 8 43 0 8 15 0 8 0 36 8 0 0 8 0 15 % G
% His: 0 0 0 0 0 0 0 8 8 0 0 0 0 0 8 % H
% Ile: 0 0 0 0 0 8 0 0 8 0 0 8 8 0 0 % I
% Lys: 0 0 0 29 43 22 36 15 0 72 8 8 8 15 0 % K
% Leu: 0 0 8 0 8 22 8 0 8 0 0 0 0 0 36 % L
% Met: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 15 % M
% Asn: 0 8 0 0 8 0 0 8 22 0 8 8 8 43 0 % N
% Pro: 8 8 0 0 0 8 0 8 0 0 0 0 0 0 8 % P
% Gln: 0 0 0 15 0 0 15 0 0 0 0 0 0 8 0 % Q
% Arg: 0 0 15 0 0 0 0 0 0 0 0 8 50 8 0 % R
% Ser: 22 0 29 15 0 8 0 43 8 0 65 50 0 8 8 % S
% Thr: 0 0 0 0 0 8 0 0 0 0 8 8 0 8 0 % T
% Val: 0 8 8 0 0 0 0 0 0 0 0 0 8 0 0 % V
% Trp: 0 8 0 0 0 0 8 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _