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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MPHOSPH10
All Species:
13.03
Human Site:
S252
Identified Species:
22.05
UniProt:
O00566
Number Species:
13
Phosphosite Substitution
Charge Score:
0.31
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00566
NP_005782.1
681
78864
S252
D
E
G
G
L
F
G
S
K
K
L
K
S
G
K
Chimpanzee
Pan troglodytes
XP_515539
681
78871
S252
D
E
G
G
L
F
G
S
K
K
L
K
S
G
K
Rhesus Macaque
Macaca mulatta
XP_001102757
682
78836
S253
D
E
G
G
L
F
G
S
K
K
L
K
S
G
K
Dog
Lupus familis
XP_849351
676
78277
S251
D
E
G
E
L
F
G
S
Q
K
P
K
S
G
K
Cat
Felis silvestris
Mouse
Mus musculus
Q810V0
681
78656
R254
S
E
G
G
L
F
G
R
Q
K
I
K
S
N
K
Rat
Rattus norvegicus
NP_001099810
676
77809
L251
S
D
E
N
E
G
G
L
F
G
K
Q
K
I
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509780
472
52873
R81
A
G
A
T
W
S
W
R
G
G
E
G
P
H
E
Chicken
Gallus gallus
XP_413769
665
76446
D235
F
E
D
I
I
S
E
D
E
E
E
E
F
E
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_709654
695
79706
V253
L
S
F
D
K
P
V
V
K
K
K
L
K
N
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609237
662
76083
E236
A
D
F
F
D
M
N
E
E
L
T
E
H
S
K
Honey Bee
Apis mellifera
XP_394707
639
74546
E225
A
D
F
F
D
S
P
E
S
E
D
E
N
L
D
Nematode Worm
Caenorhab. elegans
NP_499580
648
73878
D228
D
E
E
M
M
F
E
D
E
D
S
W
D
G
K
Sea Urchin
Strong. purpuratus
XP_798175
686
78053
D248
D
D
E
D
D
D
D
D
E
E
K
Q
D
N
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P47083
593
66934
D202
R
D
T
L
A
A
E
D
S
N
E
A
S
E
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
96.3
86.1
N.A.
82.6
80.6
N.A.
43.7
61.2
N.A.
56.5
N.A.
35
43.6
32.7
41.1
Protein Similarity:
100
99.2
98.3
93.8
N.A.
90.7
89.4
N.A.
53.8
77.6
N.A.
71.8
N.A.
54.3
61.8
53.2
59.9
P-Site Identity:
100
100
100
80
N.A.
66.6
13.3
N.A.
0
6.6
N.A.
20
N.A.
6.6
0
33.3
13.3
P-Site Similarity:
100
100
100
86.6
N.A.
80
26.6
N.A.
6.6
40
N.A.
20
N.A.
26.6
26.6
46.6
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
22
0
8
0
8
8
0
0
0
0
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
43
36
8
15
22
8
8
29
0
8
8
0
15
0
8
% D
% Glu:
0
50
22
8
8
0
22
15
29
22
22
22
0
15
15
% E
% Phe:
8
0
22
15
0
43
0
0
8
0
0
0
8
0
0
% F
% Gly:
0
8
36
29
0
8
43
0
8
15
0
8
0
36
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
8
8
0
% H
% Ile:
0
0
0
8
8
0
0
0
0
0
8
0
0
8
0
% I
% Lys:
0
0
0
0
8
0
0
0
29
43
22
36
15
0
72
% K
% Leu:
8
0
0
8
36
0
0
8
0
8
22
8
0
8
0
% L
% Met:
0
0
0
8
8
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
8
0
0
8
0
0
8
22
0
% N
% Pro:
0
0
0
0
0
8
8
0
0
0
8
0
8
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
15
0
0
15
0
0
0
% Q
% Arg:
8
0
0
0
0
0
0
15
0
0
0
0
0
0
0
% R
% Ser:
15
8
0
0
0
22
0
29
15
0
8
0
43
8
0
% S
% Thr:
0
0
8
8
0
0
0
0
0
0
8
0
0
0
0
% T
% Val:
0
0
0
0
0
0
8
8
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
8
0
8
0
0
0
0
8
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _