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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MPHOSPH10 All Species: 20.3
Human Site: S163 Identified Species: 34.36
UniProt: O00566 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.23
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O00566 NP_005782.1 681 78864 S163 S K S D L R K S P V F S D E D
Chimpanzee Pan troglodytes XP_515539 681 78871 S163 S K S D L R K S P V F S D E D
Rhesus Macaque Macaca mulatta XP_001102757 682 78836 S164 S K S G L R K S P V F S D E D
Dog Lupus familis XP_849351 676 78277 S164 S K V D L R K S P V F S D E D
Cat Felis silvestris
Mouse Mus musculus Q810V0 681 78656 S164 R K S D P R K S P V F S D E D
Rat Rattus norvegicus NP_001099810 676 77809 S164 R K P D P R K S P A F S D E D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509780 472 52873
Chicken Gallus gallus XP_413769 665 76446 E155 K P R E T V I E E Y S D E D S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_709654 695 79706 E165 G E D D F S G E D S D L D F D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_609237 662 76083 K161 P P K D K R N K R L R N S V V
Honey Bee Apis mellifera XP_394707 639 74546 D149 N L K K Q K K D V R K R K K K
Nematode Worm Caenorhab. elegans NP_499580 648 73878 A146 M I D D E D E A D L F N L S E
Sea Urchin Strong. purpuratus XP_798175 686 78053 D154 S D E S G E S D T N F D I D E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P47083 593 66934 V127 K Q M L S A D V S E I E E Q S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 96.3 86.1 N.A. 82.6 80.6 N.A. 43.7 61.2 N.A. 56.5 N.A. 35 43.6 32.7 41.1
Protein Similarity: 100 99.2 98.3 93.8 N.A. 90.7 89.4 N.A. 53.8 77.6 N.A. 71.8 N.A. 54.3 61.8 53.2 59.9
P-Site Identity: 100 100 93.3 93.3 N.A. 86.6 73.3 N.A. 0 0 N.A. 20 N.A. 13.3 6.6 13.3 13.3
P-Site Similarity: 100 100 93.3 93.3 N.A. 86.6 73.3 N.A. 0 20 N.A. 26.6 N.A. 26.6 26.6 46.6 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.1 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 46.8 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 8 0 8 0 8 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 15 58 0 8 8 15 15 0 8 15 50 15 50 % D
% Glu: 0 8 8 8 8 8 8 15 8 8 0 8 15 43 15 % E
% Phe: 0 0 0 0 8 0 0 0 0 0 58 0 0 8 0 % F
% Gly: 8 0 0 8 8 0 8 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 0 0 0 0 8 0 0 0 8 0 8 0 0 % I
% Lys: 15 43 15 8 8 8 50 8 0 0 8 0 8 8 8 % K
% Leu: 0 8 0 8 29 0 0 0 0 15 0 8 8 0 0 % L
% Met: 8 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 0 0 0 0 0 8 0 0 8 0 15 0 0 0 % N
% Pro: 8 15 8 0 15 0 0 0 43 0 0 0 0 0 0 % P
% Gln: 0 8 0 0 8 0 0 0 0 0 0 0 0 8 0 % Q
% Arg: 15 0 8 0 0 50 0 0 8 8 8 8 0 0 0 % R
% Ser: 36 0 29 8 8 8 8 43 8 8 8 43 8 8 15 % S
% Thr: 0 0 0 0 8 0 0 0 8 0 0 0 0 0 0 % T
% Val: 0 0 8 0 0 8 0 8 8 36 0 0 0 8 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _