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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CACNA1A
All Species:
10.91
Human Site:
Y795
Identified Species:
24
UniProt:
O00555
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00555
NP_001120693.1
2505
282365
Y795
L
A
S
R
E
A
L
Y
N
E
M
D
P
D
E
Chimpanzee
Pan troglodytes
XP_520396
2784
310342
Y1237
R
A
S
C
E
A
L
Y
S
E
M
D
P
E
E
Rhesus Macaque
Macaca mulatta
XP_001110352
2383
269535
R781
H
M
S
V
W
E
Q
R
T
S
Q
L
R
K
H
Dog
Lupus familis
XP_537779
2046
229120
R532
F
G
G
Q
F
N
F
R
D
E
T
P
T
T
N
Cat
Felis silvestris
Mouse
Mus musculus
P97445
2368
267629
Y797
L
A
S
R
E
A
L
Y
G
D
A
A
E
R
W
Rat
Rattus norvegicus
P54282
2212
251509
V698
V
F
S
I
Y
F
I
V
L
T
L
F
G
N
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
O73700
2190
249326
L676
K
S
I
A
S
L
L
L
L
L
F
L
F
I
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_690548
2303
262065
Y779
V
N
S
R
E
A
L
Y
N
E
L
D
P
E
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91645
1851
212452
M337
Q
K
C
R
F
R
A
M
F
Q
T
A
M
V
S
Honey Bee
Apis mellifera
NP_001159376
1904
215872
F390
T
S
F
D
N
I
G
F
A
M
L
T
V
F
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001186699
1966
222605
G452
V
I
K
L
Y
G
L
G
P
G
V
Y
F
Q
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
55
55.9
54.6
N.A.
87.9
82.7
N.A.
N.A.
35.9
N.A.
72.3
N.A.
43
44.4
N.A.
39.6
Protein Similarity:
100
63.5
66.3
63.4
N.A.
89.9
84.6
N.A.
N.A.
50.4
N.A.
80
N.A.
53.9
55.4
N.A.
51.6
P-Site Identity:
100
73.3
6.6
6.6
N.A.
53.3
6.6
N.A.
N.A.
6.6
N.A.
66.6
N.A.
6.6
0
N.A.
6.6
P-Site Similarity:
100
86.6
6.6
20
N.A.
60
33.3
N.A.
N.A.
13.3
N.A.
93.3
N.A.
13.3
26.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
28
0
10
0
37
10
0
10
0
10
19
0
0
0
% A
% Cys:
0
0
10
10
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
0
0
10
10
0
28
0
10
10
% D
% Glu:
0
0
0
0
37
10
0
0
0
37
0
0
10
19
19
% E
% Phe:
10
10
10
0
19
10
10
10
10
0
10
10
19
10
0
% F
% Gly:
0
10
10
0
0
10
10
10
10
10
0
0
10
0
0
% G
% His:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
0
10
10
10
0
10
10
0
0
0
0
0
0
10
10
% I
% Lys:
10
10
10
0
0
0
0
0
0
0
0
0
0
10
0
% K
% Leu:
19
0
0
10
0
10
55
10
19
10
28
19
0
0
0
% L
% Met:
0
10
0
0
0
0
0
10
0
10
19
0
10
0
0
% M
% Asn:
0
10
0
0
10
10
0
0
19
0
0
0
0
10
10
% N
% Pro:
0
0
0
0
0
0
0
0
10
0
0
10
28
0
0
% P
% Gln:
10
0
0
10
0
0
10
0
0
10
10
0
0
10
10
% Q
% Arg:
10
0
0
37
0
10
0
19
0
0
0
0
10
10
0
% R
% Ser:
0
19
55
0
10
0
0
0
10
10
0
0
0
0
19
% S
% Thr:
10
0
0
0
0
0
0
0
10
10
19
10
10
10
0
% T
% Val:
28
0
0
10
0
0
0
10
0
0
10
0
10
10
0
% V
% Trp:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
10
% W
% Tyr:
0
0
0
0
19
0
0
37
0
0
0
10
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _