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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CACNA1A
All Species:
17.58
Human Site:
Y596
Identified Species:
38.67
UniProt:
O00555
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00555
NP_001120693.1
2505
282365
Y596
R
I
F
K
V
T
K
Y
W
A
S
L
R
N
L
Chimpanzee
Pan troglodytes
XP_520396
2784
310342
Y1040
P
T
F
K
V
T
K
Y
W
S
S
L
R
N
L
Rhesus Macaque
Macaca mulatta
XP_001110352
2383
269535
Y585
R
I
F
K
I
T
K
Y
W
A
S
L
R
N
L
Dog
Lupus familis
XP_537779
2046
229120
M364
Y
F
R
R
K
E
K
M
F
R
F
F
I
R
R
Cat
Felis silvestris
Mouse
Mus musculus
P97445
2368
267629
Y598
R
I
F
K
V
T
K
Y
W
A
S
L
R
N
L
Rat
Rattus norvegicus
P54282
2212
251509
G530
Y
A
E
F
I
F
L
G
L
F
M
S
E
M
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
O73700
2190
249326
A508
S
G
E
G
E
N
P
A
C
C
G
S
L
C
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_690548
2303
262065
Y580
R
I
F
K
V
T
K
Y
W
A
S
L
R
N
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91645
1851
212452
P168
S
I
I
K
A
M
A
P
L
L
Q
I
G
L
L
Honey Bee
Apis mellifera
NP_001159376
1904
215872
I222
C
V
E
A
S
L
K
I
L
A
L
G
F
V
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001186699
1966
222605
F284
V
S
V
L
N
R
E
F
A
K
E
R
E
R
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
55
55.9
54.6
N.A.
87.9
82.7
N.A.
N.A.
35.9
N.A.
72.3
N.A.
43
44.4
N.A.
39.6
Protein Similarity:
100
63.5
66.3
63.4
N.A.
89.9
84.6
N.A.
N.A.
50.4
N.A.
80
N.A.
53.9
55.4
N.A.
51.6
P-Site Identity:
100
80
93.3
6.6
N.A.
100
0
N.A.
N.A.
0
N.A.
100
N.A.
20
20
N.A.
0
P-Site Similarity:
100
86.6
100
20
N.A.
100
6.6
N.A.
N.A.
0
N.A.
100
N.A.
26.6
26.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
10
10
0
10
10
10
46
0
0
0
0
0
% A
% Cys:
10
0
0
0
0
0
0
0
10
10
0
0
0
10
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
28
0
10
10
10
0
0
0
10
0
19
0
0
% E
% Phe:
0
10
46
10
0
10
0
10
10
10
10
10
10
0
10
% F
% Gly:
0
10
0
10
0
0
0
10
0
0
10
10
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
46
10
0
19
0
0
10
0
0
0
10
10
0
0
% I
% Lys:
0
0
0
55
10
0
64
0
0
10
0
0
0
0
0
% K
% Leu:
0
0
0
10
0
10
10
0
28
10
10
46
10
10
64
% L
% Met:
0
0
0
0
0
10
0
10
0
0
10
0
0
10
0
% M
% Asn:
0
0
0
0
10
10
0
0
0
0
0
0
0
46
0
% N
% Pro:
10
0
0
0
0
0
10
10
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
10
% Q
% Arg:
37
0
10
10
0
10
0
0
0
10
0
10
46
19
10
% R
% Ser:
19
10
0
0
10
0
0
0
0
10
46
19
0
0
0
% S
% Thr:
0
10
0
0
0
46
0
0
0
0
0
0
0
0
0
% T
% Val:
10
10
10
0
37
0
0
0
0
0
0
0
0
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
46
0
0
0
0
0
0
% W
% Tyr:
19
0
0
0
0
0
0
46
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _