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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CACNA1A
All Species:
1.21
Human Site:
Y2139
Identified Species:
2.67
UniProt:
O00555
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00555
NP_001120693.1
2505
282365
Y2139
K
A
R
R
L
D
D
Y
S
L
E
R
V
P
P
Chimpanzee
Pan troglodytes
XP_520396
2784
310342
P2457
R
L
A
A
E
T
Q
P
V
T
D
A
S
P
M
Rhesus Macaque
Macaca mulatta
XP_001110352
2383
269535
F2034
N
S
S
W
L
E
E
F
S
M
E
R
S
S
E
Dog
Lupus familis
XP_537779
2046
229120
Q1719
P
R
L
A
A
E
T
Q
P
A
P
D
A
S
P
Cat
Felis silvestris
Mouse
Mus musculus
P97445
2368
267629
Q2039
H
Y
L
P
M
E
G
Q
T
R
A
A
S
M
P
Rat
Rattus norvegicus
P54282
2212
251509
L1885
M
M
A
I
W
P
N
L
S
Q
K
T
L
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
O73700
2190
249326
C1863
E
R
D
I
R
D
Y
C
N
D
D
H
Y
L
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_690548
2303
262065
A1973
A
S
M
P
R
L
P
A
D
N
Q
P
R
R
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91645
1851
212452
T1524
H
P
S
Q
E
S
L
T
G
A
D
A
G
H
L
Honey Bee
Apis mellifera
NP_001159376
1904
215872
S1577
E
L
R
D
T
I
R
S
I
W
P
L
Q
A
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001186699
1966
222605
H1639
D
P
D
R
E
S
R
H
H
R
Y
R
E
P
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
55
55.9
54.6
N.A.
87.9
82.7
N.A.
N.A.
35.9
N.A.
72.3
N.A.
43
44.4
N.A.
39.6
Protein Similarity:
100
63.5
66.3
63.4
N.A.
89.9
84.6
N.A.
N.A.
50.4
N.A.
80
N.A.
53.9
55.4
N.A.
51.6
P-Site Identity:
100
6.6
26.6
6.6
N.A.
6.6
6.6
N.A.
N.A.
6.6
N.A.
0
N.A.
0
6.6
N.A.
26.6
P-Site Similarity:
100
20
60
13.3
N.A.
26.6
26.6
N.A.
N.A.
26.6
N.A.
13.3
N.A.
13.3
13.3
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
19
19
10
0
0
10
0
19
10
28
10
10
0
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% C
% Asp:
10
0
19
10
0
19
10
0
10
10
28
10
0
10
0
% D
% Glu:
19
0
0
0
28
28
10
0
0
0
19
0
10
0
10
% E
% Phe:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
10
0
10
0
0
0
10
0
10
% G
% His:
19
0
0
0
0
0
0
10
10
0
0
10
0
10
0
% H
% Ile:
0
0
0
19
0
10
0
0
10
0
0
0
0
0
0
% I
% Lys:
10
0
0
0
0
0
0
0
0
0
10
0
0
0
19
% K
% Leu:
0
19
19
0
19
10
10
10
0
10
0
10
10
10
19
% L
% Met:
10
10
10
0
10
0
0
0
0
10
0
0
0
10
10
% M
% Asn:
10
0
0
0
0
0
10
0
10
10
0
0
0
0
0
% N
% Pro:
10
19
0
19
0
10
10
10
10
0
19
10
0
28
37
% P
% Gln:
0
0
0
10
0
0
10
19
0
10
10
0
10
0
0
% Q
% Arg:
10
19
19
19
19
0
19
0
0
19
0
28
10
10
0
% R
% Ser:
0
19
19
0
0
19
0
10
28
0
0
0
28
19
0
% S
% Thr:
0
0
0
0
10
10
10
10
10
10
0
10
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
10
0
0
0
10
0
0
% V
% Trp:
0
0
0
10
10
0
0
0
0
10
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
10
10
0
0
10
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _