KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CACNA1A
All Species:
6.06
Human Site:
Y1439
Identified Species:
13.33
UniProt:
O00555
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00555
NP_001120693.1
2505
282365
Y1439
R
D
R
E
W
K
K
Y
E
F
H
Y
D
N
V
Chimpanzee
Pan troglodytes
XP_520396
2784
310342
Y1792
Q
P
R
Q
W
K
K
Y
D
F
H
Y
D
N
V
Rhesus Macaque
Macaca mulatta
XP_001110352
2383
269535
H1348
K
G
R
E
W
K
R
H
E
F
H
Y
D
N
I
Dog
Lupus familis
XP_537779
2046
229120
D1056
P
R
Q
W
K
K
Y
D
F
H
Y
D
N
V
L
Cat
Felis silvestris
Mouse
Mus musculus
P97445
2368
267629
K1371
F
E
R
D
C
R
G
K
Y
L
L
Y
E
K
N
Rat
Rattus norvegicus
P54282
2212
251509
A1222
E
D
P
V
Q
P
N
A
P
R
N
N
V
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
O73700
2190
249326
A1200
Q
R
Q
C
V
E
Y
A
L
K
A
R
P
L
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_690548
2303
262065
E1309
L
V
Y
E
R
D
N
E
V
R
S
Q
K
R
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91645
1851
212452
S861
G
F
D
M
S
G
S
S
A
G
Q
N
L
S
T
Honey Bee
Apis mellifera
NP_001159376
1904
215872
L914
I
S
L
S
S
I
A
L
A
A
E
D
P
V
W
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001186699
1966
222605
Y976
E
E
E
C
Q
G
R
Y
F
L
Y
E
G
D
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
55
55.9
54.6
N.A.
87.9
82.7
N.A.
N.A.
35.9
N.A.
72.3
N.A.
43
44.4
N.A.
39.6
Protein Similarity:
100
63.5
66.3
63.4
N.A.
89.9
84.6
N.A.
N.A.
50.4
N.A.
80
N.A.
53.9
55.4
N.A.
51.6
P-Site Identity:
100
73.3
66.6
6.6
N.A.
13.3
6.6
N.A.
N.A.
0
N.A.
6.6
N.A.
0
0
N.A.
6.6
P-Site Similarity:
100
93.3
93.3
33.3
N.A.
40
13.3
N.A.
N.A.
20
N.A.
6.6
N.A.
6.6
0
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
10
19
19
10
10
0
0
0
0
% A
% Cys:
0
0
0
19
10
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
19
10
10
0
10
0
10
10
0
0
19
28
10
0
% D
% Glu:
19
19
10
28
0
10
0
10
19
0
10
10
10
0
10
% E
% Phe:
10
10
0
0
0
0
0
0
19
28
0
0
0
0
0
% F
% Gly:
10
10
0
0
0
19
10
0
0
10
0
0
10
0
0
% G
% His:
0
0
0
0
0
0
0
10
0
10
28
0
0
0
0
% H
% Ile:
10
0
0
0
0
10
0
0
0
0
0
0
0
0
10
% I
% Lys:
10
0
0
0
10
37
19
10
0
10
0
0
10
10
0
% K
% Leu:
10
0
10
0
0
0
0
10
10
19
10
0
10
19
10
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
19
0
0
0
10
19
10
28
10
% N
% Pro:
10
10
10
0
0
10
0
0
10
0
0
0
19
0
0
% P
% Gln:
19
0
19
10
19
0
0
0
0
0
10
10
0
0
10
% Q
% Arg:
10
19
37
0
10
10
19
0
0
19
0
10
0
10
19
% R
% Ser:
0
10
0
10
19
0
10
10
0
0
10
0
0
10
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% T
% Val:
0
10
0
10
10
0
0
0
10
0
0
0
10
19
19
% V
% Trp:
0
0
0
10
28
0
0
0
0
0
0
0
0
0
10
% W
% Tyr:
0
0
10
0
0
0
19
28
10
0
19
37
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _