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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CACNA1A
All Species:
11.82
Human Site:
S753
Identified Species:
26
UniProt:
O00555
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O00555
NP_001120693.1
2505
282365
S753
V
A
E
V
S
P
L
S
A
A
N
M
S
I
A
Chimpanzee
Pan troglodytes
XP_520396
2784
310342
P1195
K
E
V
A
E
V
S
P
M
S
A
A
N
I
S
Rhesus Macaque
Macaca mulatta
XP_001110352
2383
269535
S739
A
K
E
V
S
P
M
S
A
P
N
M
P
S
I
Dog
Lupus familis
XP_537779
2046
229120
R490
T
K
Y
W
S
S
L
R
N
L
V
V
S
L
L
Cat
Felis silvestris
Mouse
Mus musculus
P97445
2368
267629
S755
V
A
E
V
S
P
L
S
A
A
N
M
S
I
A
Rat
Rattus norvegicus
P54282
2212
251509
F656
P
P
T
N
F
D
T
F
P
A
A
I
M
T
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
O73700
2190
249326
L634
E
L
E
I
M
S
P
L
G
I
S
V
F
R
C
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_690548
2303
262065
S737
V
A
E
V
S
P
L
S
A
A
N
L
S
I
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91645
1851
212452
P295
F
N
W
I
Y
F
V
P
L
I
V
I
G
S
F
Honey Bee
Apis mellifera
NP_001159376
1904
215872
P348
K
E
G
E
Q
A
S
P
C
N
T
D
N
K
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001186699
1966
222605
N410
V
I
V
L
V
F
L
N
T
I
C
V
A
I
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
55
55.9
54.6
N.A.
87.9
82.7
N.A.
N.A.
35.9
N.A.
72.3
N.A.
43
44.4
N.A.
39.6
Protein Similarity:
100
63.5
66.3
63.4
N.A.
89.9
84.6
N.A.
N.A.
50.4
N.A.
80
N.A.
53.9
55.4
N.A.
51.6
P-Site Identity:
100
6.6
53.3
20
N.A.
100
6.6
N.A.
N.A.
6.6
N.A.
93.3
N.A.
0
0
N.A.
20
P-Site Similarity:
100
26.6
60
33.3
N.A.
100
13.3
N.A.
N.A.
26.6
N.A.
100
N.A.
20
13.3
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
28
0
10
0
10
0
0
37
37
19
10
10
0
28
% A
% Cys:
0
0
0
0
0
0
0
0
10
0
10
0
0
0
10
% C
% Asp:
0
0
0
0
0
10
0
0
0
0
0
10
0
0
0
% D
% Glu:
10
19
46
10
10
0
0
0
0
0
0
0
0
0
10
% E
% Phe:
10
0
0
0
10
19
0
10
0
0
0
0
10
0
10
% F
% Gly:
0
0
10
0
0
0
0
0
10
0
0
0
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
19
0
0
0
0
0
28
0
19
0
46
10
% I
% Lys:
19
19
0
0
0
0
0
0
0
0
0
0
0
10
0
% K
% Leu:
0
10
0
10
0
0
46
10
10
10
0
10
0
10
10
% L
% Met:
0
0
0
0
10
0
10
0
10
0
0
28
10
0
0
% M
% Asn:
0
10
0
10
0
0
0
10
10
10
37
0
19
0
0
% N
% Pro:
10
10
0
0
0
37
10
28
10
10
0
0
10
0
0
% P
% Gln:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
10
0
0
0
0
0
10
0
% R
% Ser:
0
0
0
0
46
19
19
37
0
10
10
0
37
19
19
% S
% Thr:
10
0
10
0
0
0
10
0
10
0
10
0
0
10
0
% T
% Val:
37
0
19
37
10
10
10
0
0
0
19
28
0
0
10
% V
% Trp:
0
0
10
10
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
10
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _